Sensitive fluorescent detection of methyltransferase based on thermosensitive poly(N-isopropylacrylamide)

Niu, Longqing; Wang, Xinxin; Mao, Guobin; Li, Zheng; Ji, Xinghu; He, Zhike

doi:10.1016/j.talanta.2018.07.026

Cited by 3 publications

(1 citation statement)

References 33 publications

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“…Experimental data showed that the detection limit of the sensor was as low as 0.18 U/ml, which indicated that the method had high sensitivity and selectivity for the detection of DNA methylation and M. SssI MTase activity. This highly sensitive biosensor can be used as a useful tool in diagnostic and biomedical research ( Niu et al, 2018 ). In 2020, Li et al first used manganese acetylacetone (III) as a single precursor to synthesize manganese oxide-doped CDs (MnOx-CDs).…”

Section: Applications In Biomedical Fieldmentioning

confidence: 99%

Nanomaterials based on thermosensitive polymer in biomedical field

et al. 2022

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The progress of nanotechnology enables us to make use of the special properties of materials on the nanoscale and open up many new fields of biomedical research. Among them, thermosensitive nanomaterials stand out in many biomedical fields because of their “intelligent” behavior in response to temperature changes. However, this article mainly reviews the research progress of thermosensitive nanomaterials, which are popular in biomedical applications in recent years. Here, we simply classify the thermally responsive nanomaterials according to the types of polymers, focusing on the mechanisms of action and their advantages and potential. Finally, we deeply investigate the applications of thermosensitive nanomaterials in drug delivery, tissue engineering, sensing analysis, cell culture, 3D printing, and other fields and probe the current challenges and future development prospects of thermosensitive nanomaterials.

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Section: Applications In Biomedical Fieldmentioning

confidence: 99%

Nanomaterials based on thermosensitive polymer in biomedical field

et al. 2022

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A smart MXene-copolymeric molecularly imprinted hydrogel with dual-response and photothermal conversion performance for specific recognition of cis-diol compounds

et al. 2021

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Carbon-based SERS biosensor: from substrate design to sensing and bioapplication

et al. 2021

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The sensing of bioactive molecules based on photochemical techniques has become one of the fastest-growing scientific fields. Surface-enhanced Raman scattering (SERS) is a highly sensitive technique for the detection of low-concentration molecules, including DNA, microRNA, proteins, blood, and bacteria; single-cell detection and identification; bioimaging; and disease diagnosis, providing abundant structural information for biological analytes. One rapidly developing field of SERS biosensor design is the use of carbon-based nanomaterials as substrate materials, such as zero-dimensional carbon quantum dots, one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide (GO) and three-dimensional spatial carbon nanomaterials or carbon-based core-shell nanostructures. In this review, we describe the recent developments in SERS biosensors, in particular carbon-based SERS, for the detection of bioactive molecules. We systematically survey recent developments in carbon nanomaterial-based SERS biosensors, focusing on fundamental principles for carbon-based materials for SERS biosensor design, fabrication, and operation, and provide insights into their rapidly growing future potential in the fields of biomedical and biological engineering, in situ analysis, quantitative analysis, and flexible photoelectric functional materials. As such, this review can play the role of a roadmap to guide researchers toward concepts that can be used in the design of next-generation SERS biosensors while also highlighting current advancements in this field.

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Sensitive fluorescent detection of methyltransferase based on thermosensitive poly(N-isopropylacrylamide)

Cited by 3 publications

References 33 publications

Nanomaterials based on thermosensitive polymer in biomedical field

Nanomaterials based on thermosensitive polymer in biomedical field

A smart MXene-copolymeric molecularly imprinted hydrogel with dual-response and photothermal conversion performance for specific recognition of cis-diol compounds

Carbon-based SERS biosensor: from substrate design to sensing and bioapplication

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