Sensorineural hearing loss and type II diabetes mellitus

Abstract

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">The association between Hearing loss and diabetes, first mentioned by Jardao in 1857, had been under continuous research since then; giving both positive and negative results. This study aims to explore the relationship of hearing loss with type II DM and also to evaluate the impact of glycemic control over degree of hearing loss. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">92 patients with type II DM were enrolled in this study, audiometrically evaluated and compared with equal number of age and sex matched non-diabetic controls. Apart from audiological tests, haematological tests like FBS, PPBS, HbA1c, serum creatinine and cholesterol were carried out to assess glycemic control. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">It was observed that 31 (34%) of the diabetic patients had mild to moderate sensorineural hearing loss, while only 12 (13%) of the control group suffered from the same, which is statistically significant (p<0.05). Among these 31 patients, 19 (61%) patients had uncontrolled diabetes (HbA1c >8.5) and 12 (39%) had higher creatinine levels (>2.5 mg/dl). Higher frequencies (4 and 8 kHz) were found to be affected more, both in case and control groups. Low stapedial reflex thresholds were observed in 14% patients of case group and 5.4% of the controls. Speech discrimination scores were not significantly different. Otoacoustic emission showed outer hair cell dysfunction in 85% cases and 66% controls. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">There is a strong correlation between diabetes mellitus and hearing threshold levels especially at higher frequencies. Long duration and uncontrolled diabetes has more implications over hearing threshold. Since the pattern of hearing loss in diabetes and presbycusis is similar, it may be said that hearing level with ageing is significantly impaired earlier in diabetic patients as compared to general population.</span></p>

Prevalence of hearing impairment in patients with diabetes mellitus at tertiary care center of Nepal

“…Our finding was in concordance with previous studies conducted in India. 18,25 Dosemane et al, 17 asserted that there were far lesser complaints of ear problems (39%) by diabetes mellitus patients when contested to the actual prevalence (97.2%) in terms of audiological evaluation in their South Indian study population. Corroborating to Dosemane et al, 17 Soares et al, 26 observed that the prevalence of hearing loss in diabetes mellitus patients was quite low( 2.56%) when it was self-reported.…”

“…This finding was less compared to earlier studies where the prevalence of hearing loss in diabetes mellitus patients quoted from a range of 33.7% to 97.6%. [15][16][17][18][19] We did not find clarification for such a broad variation, but it could be attributed to the study methodology of differences in inclusion criteria, demographics, type and duration of diabetes mellitus, the clinical and biochemical status of diabetes mellitus patients. The current study did not limit the recruitment of study participants according to the duration of disease, age, or gender.…”

Hubungan Diabetes Melitus Tipe-2 Dengan Terjadinya Gangguan Pendengaran

“…Hal ini sesuai dengan penelitian yang dilakukan oleh Kavita Sachdeeva yang menyatakan derajat gangguan pendengaran ditemukan lebih sedikit pada kelompok kontrol yaitu 21% pada derajat ringan dan 7% derajat sedang, dibandingkan dengan kelompok penderita DM Tipe-2 di mana 42% mengalami derajat ringan dan 30% mengalami derajat berat. 17 Peningkatan ambang dengar dikaitkan dengan kejadian mkiroangiopati mikrovaskular pada kapiler stria vaskularis, dimana terjadi penebalan dari pembuluh darah ini dibandingkan dengan keadaan normal. Sebagian besar penderita DM Tipe-2 dengan tuli sensorineural memiliki gangguan pendengaran derajat ringan sampai sedang atau sedang berat.…”

“…18 Penelitian yang dilakukan oleh Kavita Sachdeva menyatakan bahwa semakin lama menderita DM akan semakin tinggi kemungkinan untuk mengalami gangguan pendengaran. 17 Penelitian ini memiliki banyak kelemahan dikarenakan adanya keterbatasan pada penulis. Kelemahan tersebut diantaranya adalah, sampel yang digunakan dalam penelitian ini hanya dilakukan di Rumah sakit Bhayangkara TK II Medan, sehingga hasil yang didapat mungkin akan menimbulkan perbedaan apabila dilakukan pada rumah sakit lain.…”

Audiometric studies in type 2 diabetes mellitus

“…In 1857, Jardao for the first time mentioned the association between diabetes and hearing loss. [4] A meta-analysis of 18 clinical studies have reported association between diabetes and hearing loss [5] whereas many others have found no association between the two conditions. [6] Presence of confounding factors and complexity of auditory canal represent the pitfalls in estimating the affect of diabetes on hearing loss.…”