Separate Progenitors for Radial and Tangential Cell Dispersion during Development of the Cerebral Neocortex

Tan, Seong‐Seng; Kalloniatis, Michael; Sturm, Karin S.; Tam, Patrick; Reese, Benjamin E.; Faulkner-Jones, Beverly E.

doi:10.1016/s0896-6273(00)80539-5

Cited by 220 publications

(150 citation statements)

References 57 publications

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“…In contrast to these views, previous studies, from the classical ones of His (1887) and Cajal (1911) to more recent ones (Levitt et al, 1981;Grove et al, 1993;Tan et al, 1998; There is a statistically significant difference in the size of sodium current (*p ϭ 0.0126), but not in potassium current ( p ϭ 0.3798). Error bars represent SEM.…”

Section: Multipotent Progenitor Cellsmentioning

confidence: 82%

“…Neural stem cells in rodents include temporally and regionally restricted subpopulations from the very beginning of corticogenesis (Grove et al, 1993;Tan et al, 1998;McCarthy et al, 2001;Temple, 2001;Temple, 2006, Maric et al, 2007). In the mouse VZ, two precursor subclasses, distinct neuronal precursors and RG cells, were discerned using in utero electroporation with different reporter constructs (Gal et al, 2006).…”

Section: Neuron-restricted Progenitorsmentioning

confidence: 99%

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Human Cortical Neurons Originate from Radial Glia and Neuron-Restricted Progenitors

Mo¹,

Moore²,

Filipovic³

et al. 2007

J. Neurosci.

103

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Understanding the molecular and physiological determinants of cortical neuronal progenitor cells is essential for understanding the development of the human brain in health and in disease. We used surface marker fucose N-acetyl lactosamine (LeX) (also known as CD15) to isolate progenitor cells from the cortical ventricular/subventricular zone of human fetal brain at the second trimester of gestation and to study their progeny in vitro.

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Section: Multipotent Progenitor Cellsmentioning

confidence: 82%

Section: Neuron-restricted Progenitorsmentioning

confidence: 99%

Human Cortical Neurons Originate from Radial Glia and Neuron-Restricted Progenitors

Mo¹,

Moore²,

Filipovic³

et al. 2007

J. Neurosci.

103

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“…Glutamate neurons are thought to arise from the dorsal PVE by radial migration into the cortical plate, whereas GABAergic interneurons may reach the cortex by tangential migration from the developing basal ganglia (Luskin et al, 1988;de Carlos et al, 1996;Anderson et al, 1997a;Tan et al, 1998;Lavdas et al, 1999). To what extent the dorsal PVE may contribute to the GABAergic population is unclear.…”

Section: Discussionmentioning

confidence: 99%

“…The dorsal PVE is thought to contribute mainly to glutamatergic pyramidal cells that migrate radially from the dorsal neuroepithelium to the cortical plate (Tan et al, 1998). In contrast, a large percentage of cortical interneurons migrate tangentially to the developing cerebral cortex from the developing basal ganglia (de Carlos et al, 1996;Anderson et al, 1997a,b;Lavdas et al, 1999).…”

mentioning

confidence: 99%

Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex

et al. 2002

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Basic fibroblast growth factor (Fgf2) is required for the generation of founder cells within the dorsal pseudostratified ventricular epithelium, which will generate the cerebral cortex, but the ganglionic eminences are not affected. We report here that the Fgf2 null mutant mice show an ϳ40% decrease in cortical glutamatergic pyramidal neurons. In contrast, no change in pyramidal or granule cell number is detected in the hippocampus of Fgf2 Ϫ/Ϫ mice. In addition, the soma of the pyramidal cells in the frontal and parietal cortices are smaller in Fgf2 knock-out mice. The decrease in the number and size of glutamatergic neuronal population affects all cortical layers but is restricted to the frontal and parietal cortices without any change in the occipital cortex, indicating that Fgf2 is necessary to regulate cell number and size in the anterior cerebral cortex. In contrast to pyramidal neurons, cortical GABA interneurons are unaffected by the lack of Fgf2. The resulting imbalance between the excitatory and inhibitory neurotransmission in the cerebral cortex is reflected by an increased duration of sleep when the animals receive a GABA receptor agonist. Thus, Fgf2 signaling may contribute to the regional specification of the cerebral cortex and may play a role in increasing the size of anterior cortical regions during vertebrate evolution.

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“…Accordingly, there is to date no evidence whatsoever corroborating the speci¢c migrations postulated within Karten's (1969Karten's ( , 1991Karten's ( , 1997 hypothesis, although the experiments of Anderson et al (1997) did prove that massive tangential migrations of interneurons colonizing the cortex are possible. Glutamatergic cortical neurons (pyramidal cells and spiny stellate interneurons) meanwhile are thought to originate within the radially corresponding part of the cortical ventricular zone (Mione et al 1994;Tan et al 1998;Anderson et al 1999). An alternative source for hypopallial cells that might move into the isocortex only came into the foreground as developmental genes began to be mapped and compared in the telencephalon of several vertebrates.…”

Section: The Pallium In Sauropsidsmentioning

confidence: 99%

Thoughts on the development, structure and evolution of the mammalian and avian telencephalic pallium

Puelles

2001

Phil. Trans. R. Soc. Lond. B

175

207

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Various lines of evidence suggest that the development and evolution of the mammalian isocortex cannot be easily explained without an understanding of correlative changes in surrounding areas of the telencephalic pallium and subpallium. These are close neighbours in a common morphogenetic ¢eld and are postulated as sources of some cortical neuron types (and even of whole cortical areas). There is equal need to explain relevant developmental evolutionary changes in the dorsal thalamus, the major source of a¡erent inputs to the telencephalon (to both the pallium and subpallium). The mammalian isocortex evolved within an initially small dorsal part of the pallium of vertebrates, surrounded by other pallial parts, including some with a non-cortical, nuclear structure. Nuclear pallial elements are markedly voluminous in reptiles and birds, where they build the dorsal ventricular ridge, or hypopallium, which has been recently divided molecularly and structurally into a lateral pallium and a ventral pallium. A¡erent pallial connections are often simpli¢ed as consisting of thalamic ¢bres that project either to focal cell aggregates in the ventral pallium (predominant in reptiles and birds) or to corticoid areas in the dorsal pallium (predominant in mammals). Karten's hypothesis, put forward in 1969, on the formation of some isocortical areas postulates an embryonic translocation into the nascent isocortex of the ventropallial thalamorecipient foci and respective downstream ventropallial target populations, as speci¢c layer IV, layers II^III, or layers V^VI neuron populations. This view is considered critically in the light of various recent data, contrasting with the alternative possibility of a parallel, separate evolution of the di¡erent pallial parts. The new scenario reveals as well a separately evolving tiered structure of the dorsal thalamus, some of whose parts receive input from midbrain sensory centres (collothalamic nuclei), whereas other parts receive oligosynaptic`lemniscal' connections bypassing the midbrain (lemnothalamic nuclei). An ampler look into known hodological patterns from this viewpoint suggests that ancient collothalamic pathways, which target ventropallial foci, are largely conserved in mammals, while some emergent cortical connections can be established by means of new collaterals in some of these pathways. The lemnothalamic pathways, which typically target ancestrally the dorsopallial isocortex, show parallel increments of relative size and structural diversi¢cation of both the thalamic cell populations and the cortical recipient areas. The evolving lemnothalamic pathways may interact developmentally with collothalamic corticopetal collaterals in the modality-speci¢c invasion of the emergent new areas of isocortex.

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Separate Progenitors for Radial and Tangential Cell Dispersion during Development of the Cerebral Neocortex

Cited by 220 publications

References 57 publications

Human Cortical Neurons Originate from Radial Glia and Neuron-Restricted Progenitors

Human Cortical Neurons Originate from Radial Glia and Neuron-Restricted Progenitors

Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex

Thoughts on the development, structure and evolution of the mammalian and avian telencephalic pallium

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