Sequence analysis of Mucin 13 gene region associated with piglet diarrhoea in Indian pigs

Abstract

The current study was undertaken for characterization and bioinformatics analysis of a region of Mucin 13 gene (MUC13) associated with piglet diarrhoea in Indian native pig (Sus scrofa). A total of five gene segments ( three at intron 6 and two at exon 7-8 regions) were sequenced in pig population. The sequences were compared with available sequences of other pig population (Chinese pig), sheep, goat and cattle. As expected, high level of genetic similarity was seen between Indian pig and Chinese pig. Sequences of all five alleles were submitted to the NCBI with accession numbers KX686556 and KX686558-61. Reported genetic variability in MUC13 gene can be helpful in enhancing our understanding about the genetics of piglet diarrhoea resistance and susceptibility in Indian pig population.