Sequence-defined oligomer as a modular platform for selective sub-picomolar detection and removal of Hg²⁺

Abstract

A modular synthetic platform for selective sensing and removal of Hg2+ was developed. This modular system possesses a unique feature to gradually improve the sensitivity even in competitive environments via...

Shaping Macromolecules for Sensing Applications—From Polymer Hydrogels to Foldamers

“…Thanks to the structural control of foldamers, they can be designed to bind complementary guests [ 178 ], e.g., cations [ 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 ], anions [ 186 , 187 , 188 , 189 , 190 , 191 , 192 ], or non-charged molecules [ 164 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 ]. They have been applied in the detection of metal ions [ 210 , 211 , 212 , 213 ], explosives [ 214 ], biomarkers [ 215 ], pH [ 216 , 217 ], membrane curvature [ 218 ], and fructose [ 198 ] ( Table 3 ).…”

Efficient mercury removal in 30 seconds by designing a dithiocarbamate-based organic polymer with customizable functionalities and tunable properties

“…26 Hence, it is highly recommended to remove mercuric ions before conversion to methylmercury. Chemical precipitation, 27 electrolysis, 28 ion exchange method 29 etc. are a few techniques to remove mercury.…”

Backbone and side chain-linker tunability among dithiocarbamate, ester and amide in sequence-defined oligomers: synthesis and structure–property–function relationship

“…Taking inspiration from natural sequence-defined polymers (SDPs), like nucleic acids and peptides, materials are being designed by the sequential addition of specific monomers at preordained positions. This results in synthetic SDPs [1][2][3][4][5][6][7][8][9] with pendant group functionality, desirable chain length and defined monomeric sequence. However, all of the reports on the synthesis of SDPs focus on the same backbone with different hanging residues for a specific SDP class.…”

“…All three SDO classes have provision to incorporate a wide range of sidechain functional groups. The rationale behind keeping DTC constant in all of the SDO scaffolds is that DTC is an excellent candidate for both material (e.g., heavy metal sensor 5 and vulcanization accelerators in rubber industries 14 ) and biomedical (e.g., antileishmanial agents, 15 anti-acute myelogenous leukaemia agents, 16 antitrypanosomatids, 17 anticancer 18 ) applications. This strategy for the synthesis of SDOs thus has a unique advantage of changing both the backbone as well as the side chain.…”

“…The rationale behind keeping DTC constant in all of the SDO scaffolds is that DTC is an excellent candidate for both material ( e.g. , heavy metal sensor 5 and vulcanization accelerators in rubber industries 14 ) and biomedical ( e.g. , antileishmanial agents, 15 anti-acute myelogenous leukaemia agents, 16 antitrypanosomatids, 17 anticancer 18 ) applications.…”