Seroprevalence of hepatitis A infection in a low endemicity country: a systematic review

Pham, Ba’; Duval, Bernard; Serres, Gaston De; Gîlca, Vladimir; Tricco, Andrea C.; J, Ochnio; Scheifele, David W.

doi:10.1186/1471-2334-5-56

Cited by 41 publications

(37 citation statements)

References 40 publications

(61 reference statements)

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“…Homosexuality, travel to endemic area were found related with the seropositivity. The major risk for low endemic countries is an outbreak of the infection [16,17]. This study shows higher seropositivity than more developed foreign countries, similar to other studies from Turkey.…”

Section: Discussionsupporting

confidence: 89%

“…The change in seropositivity was associated with the development of Korea accompanied by an improvement in Age group n Anti HAV IgG positivity in Usak n (%) individual and social hygiene [14,15]. Pham et al [16] showed that the seropositivity of HAV in Canada was 1% in 8-13 ages group and increasing up to 17 % in 30-39 years group. These results are lower than those obtained from our country and also from those obained from Cyprus, Singapore and Korea.…”

Section: Discussionmentioning

confidence: 98%

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Hepatitis A seropositivity: comparative results of two hospitals in Turkey

Ağca¹

2013

JCAM

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Anahtar KelimelerHepatit A; Hijyen; Seropozitiflik Abstract Aim: Hepatitis A virus (HAV) is a ribonucleic acid (RNA) picornavirus transmitted by fecal-oral route. HAV is usually silent or subclinic in children and on a worldwide scale only 5 % of infections are recognised clinically. In this study we aimed to determine the seroprevalance of HAV seropositivity in two different hospitals in the Aegean region of Turkey. Material and Method: Serum samples, which were taken from patients to investigate hepatitis A antibodies administrated to Usak State Hospital and Tavsanli Doc. Dr. M. Kalemli State Hospital between January 2011 and December 2011 were investigated for hepatitis A seropositivity retrospectively. Age, sex, Anti HAV Ig G and Anti HAV Ig M were investigated. Results: 799 patients in Usak State Hospital and 461 patients in Tavsanli State hospital were investigated for Anti HAV Ig G and Anti HAV Ig M. 78 % were female, 22 % were male and mean age was 27,7 in Usak State Hospital. 54 % were female, 46 % were male, mean age was 38,0 in Tavsanli State Hospital. Anti-HAV Ig M positivity in Usak and Tavsanli State Hospital are 1,3 % and 0,6 % respectively. Anti-HAV Ig G positivity in Usak and Tavsanli State Hospital are 75,5 % and 80,4 % respectively. Discussion: Improvement of public and individual hygiene, education about hygiene, improvement of education and socioeconomic level of public and vaccination against HAV as recommended by the World Health Organisation may decrease the burden of HAV infection.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 98%

Hepatitis A seropositivity: comparative results of two hospitals in Turkey

Ağca¹

2013

JCAM

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“…Without vaccination, HAV causes 692 424 cases in Indonesia where the disease acquisition occurs in adulthood rather than childhood as a typical of hepatitis A case in a low endemicity country. 12 Applying a vaccine coverage at 80%, vaccination of 4 200 000 infants would reduce HAV-cases by 452 834 and 322 207 for vaccination with the two-dose and one-dose vaccine schedules, respectively. Also, the cost-effectiveness analyses yielded ICERs from the societal perspective at US$ 7421 and US$ 4933 per QALY gained for both vaccine schedules.…”

Section: Discussionmentioning

confidence: 99%

Cost-effectiveness of hepatitis A vaccination in Indonesia

Suwantika

Beutels

Postma

2014

Human Vaccines & Immunotherapeutics

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“…One confirmed case consumed the product after the recall had been issued, suggesting incomplete penetration of public health messaging. While the number of annual reported cases of hepatitis A is low in BC, seroprevalence of anti-HAV antibodies is also low [28], leading to the ongoing potential for outbreaks.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis A outbreak in British Columbia, Canada: the roles of established surveillance, consumer loyalty cards and collaboration, February to May 2012

et al. 2014

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Non-travel-related hepatitis A is rare in Canada. We describe a hepatitis A outbreak investigation in British Columbia in February to May 2012 in which exposure history was collected from nine confirmed non-travel-related cases. Suspected foods were tested for hepatitis A virus (HAV): a frozen fruit blend was identified as a common exposure for six of the nine cases using supermarket loyalty cards. Consumption of the product was confirmed in each case. Genetic analysis confirmed HAV genotype 1B in the six exposed cases. Of the three non-exposed cases, the virus could not be genotyped for two of them; the virus from the other case was found to be genotype 1A and this case was therefore not considered part of the outbreak. HAV was detected by PCR from pomegranate seeds, a component of the identified frozen fruit blend. Historically low levels of HAV infection in British Columbia triggered early recognition of the outbreak. Loyalty card histories facilitated product identification and a trace-back investigation implicated imported pomegranate seeds.

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Seroprevalence of hepatitis A infection in a low endemicity country: a systematic review

Cited by 41 publications

References 40 publications

Hepatitis A seropositivity: comparative results of two hospitals in Turkey

Hepatitis A seropositivity: comparative results of two hospitals in Turkey

Cost-effectiveness of hepatitis A vaccination in Indonesia

Hepatitis A outbreak in British Columbia, Canada: the roles of established surveillance, consumer loyalty cards and collaboration, February to May 2012

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