2016
DOI: 10.1177/1098612x15598184
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Serum cobalamin concentrations and small intestinal ultrasound changes in 75 cats with clinical signs of gastrointestinal disease: a retrospective study

Abstract: Objectives The aim of the study was to evaluate ultrasonographic changes in the small intestine of cats with clinical signs of gastrointestinal disease and low or low-normal serum cobalamin concentrations. Methods Records for client-owned cats presenting to the small animal hospital with signs of gastrointestinal disease and in which serum cobalamin concentrations were measured from 2000-2013 were reviewed. Inclusion criteria were cobalamin concentrations <500 ng/l, abdominal ultrasound within 1 month of cobal… Show more

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Cited by 16 publications
(27 citation statements)
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References 28 publications
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“…Importantly, study results suggest that an ultrasonographically normal GI tract should not preclude recommendation for intestinal biopsies in dogs with clinical signs of GI disease, as 5 dogs (38%) in the current study did not have any ultrasonographic changes to the GI tract. This has also been reported in 15% of cats with the same disease(34). Within the current study, the 5 dogs that had an ultrasonographically normal GI tract all either had significant clinical signs attributable to GI disease or hematologic and biochemical abnormalities consistent with GI disease (anemia, hypoalbuminemia, hypocobalaminemia) which lead to GI biopsies despite the lack of ultrasonographic findings.…”
Section: Discussionsupporting
confidence: 69%
See 1 more Smart Citation
“…Importantly, study results suggest that an ultrasonographically normal GI tract should not preclude recommendation for intestinal biopsies in dogs with clinical signs of GI disease, as 5 dogs (38%) in the current study did not have any ultrasonographic changes to the GI tract. This has also been reported in 15% of cats with the same disease(34). Within the current study, the 5 dogs that had an ultrasonographically normal GI tract all either had significant clinical signs attributable to GI disease or hematologic and biochemical abnormalities consistent with GI disease (anemia, hypoalbuminemia, hypocobalaminemia) which lead to GI biopsies despite the lack of ultrasonographic findings.…”
Section: Discussionsupporting
confidence: 69%
“…This has also been reported in 15% of cats with the same disease. 34 Within the current study, the 5 dogs that had an ultrasonographically normal GI tract all either had significant clinical signs attributable to GI disease or hematologic and biochemical abnormalities consistent with GI disease (anaemia, hypoalbuminemia, hypocobalaminemia) which lead to GI biopsies despite the lack of ultrasonographic findings.…”
Section: Resultsmentioning
confidence: 81%
“…Indeed, well‐recognized challenges have been reported, including shifting and controversial classification systems, evolving terminology, unsettled diagnostic criteria, and uncertain test accuracy . Distinguishing between inflammatory bowel disease and lymphoma, the 2 principal diseases affecting the feline gastrointestinal system is especially problematic and comorbidities may exist . Although cause of death was relegated to an “unknown category” whenever information was insufficient, misclassification of cause‐specific death was possible.…”
Section: Discussionmentioning
confidence: 99%
“…Cytology is not a substitute for histology, but provides clinically useful information, is fast and inexpensive. It can be used for establishing a diagnosis (e. g. adenocarcinoma, high-grade lymphoma) and a treatment plan (18,25). The infiltration of the lamina propria is of importance in establishing a histological diagnosis (5,27,33,34).…”
Section: Discussionmentioning
confidence: 99%