Serum enzymes levels and influencing factors in three indigenous Ethiopian goat breeds

Tibbo, Markos; Jibril, Yasmin; Woldemeskel, Moges; Dawo, Fufa; Aragaw, Kassaye; Rege, J.E.O.

doi:10.1007/s11250-008-9145-2

Cited by 28 publications

(20 citation statements)

References 13 publications

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“…The finding that ALP levels were higher in young goats compared to mature goats concurs with Antunovic et al (2004) who reported a decrease in ALP level with an increase in age of goats. Tibbo et al (2008) and Piccione et al (2010) had similar findings with Arsi-Bale goats of Ethiopia and Girgentana goats of Italy, respectively. In young growing animals, osseus ALP is the predominant form of serum ALP which diminishes as maturation progresses until the epishysis closes (Toba et al, 1992;Farver, 1997).…”

Section: Discussionmentioning

confidence: 54%

“…In addition, aspartate aminotransferases (AST), glutamyltransferase (GGT), alkaline phosphatase (ALP), and alanine aminotransferase (ALT), which are enzymes that are mostly produced by the liver (Smith and Sherman, 1994), are also predictive of the health status of goats (Otto et al, 2000;Ikhimioya and Imasuen, 2007;Pierce et al, 2007;Mahgoub et al, 2008). The information obtained from liver enzymes, blood minerals, and faecal egg counts substantiates the physical examination and, coupled with medical history, provides an excellent basis for estimation of severity of cases (Piccione et al, 2010) and treatment of goats (Tibbo et al, 2008). Although several studies have been conducted on blood parameter levels in goats (Pambu-Gollah et al, 2000;Kannan et al, 2003;Stella et al, 2007) and several others on the use of faecal egg counts (Hoste et al, 2005;Stella et al, 2007;Rumosa Gwaze et al, 2009a) in monitoring the health status of goats, none have been focused on the relationship between these parameters.…”

mentioning

confidence: 99%

“…If a relationship exists between any two parameters, the value of either can be used to predict the value of the other. In addition, several researchers have indicated that breed (Azab and Abdel-Maksoud, 1999;Daramola et al, 2005;Tibbo et al, 2008) modulates blood profiling values. However, a universal metabolic profile for goats cannot be established.…”

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confidence: 99%

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Effect of season and age on blood minerals, liver enzyme levels, and faecal egg counts in Nguni goats of South Africa

Gf¹,

Chimonyo²,

Dzama³

2012

Czech J. Anim. Sci.

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ABSTRACT:The objective of the study was to determine the relationships between age of the goat and faecal egg counts, liver enzymes, and minerals in the wet and dry seasons in male and female Nguni goats of South Africa. Fifty-six female and forty male Nguni goats were used for the study. Faecal and blood samples were collected once in the dry (August) and wet (January) season. Faecal egg counts (FEC) were determined by the modified McMaster technique while trematodes were determined by the sedimentation method. Blood was analyzed for phosphorus, calcium, magnesium, alkaline phosphatase (ALP), alanine transaminase (ALT), creatine kinase (CK), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) levels. Faecal egg counts were significantly higher in the wet compared with the dry season. Most (P < 0.05) of the goats were within the reference values for calcium, phosphorus, and magnesium in both seasons. Phosphorus concentrations were significantly affected by age with higher levels in the young (2.1 ± 0.06) compared to the adult (2.0 ± 0.03) goats. Alkaline phosphate was significantly affected by age with higher levels in young than in mature goats. Higher AST, CK, and GGT concentrations were recorded in the wet compared to the dry season (P < 0.05). Higher CK and AST were recorded in male than in female goats while for ALP, the values were higher in female than in male goats. Linear negative relationships (P < 0.05) existed between age and ALP, phosphorus, and FEC, while quadratic relationships existed between age and strongyles and Strongyloides egg counts. Calcium was linearly related (P < 0.05) to FEC, while CK was related to FEC in a quadratic fashion. Age of the Nguni goats can be used to predict faecal egg counts, phosphorus, and ALP levels.

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Section: Discussionmentioning

confidence: 54%

mentioning

confidence: 99%

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Effect of season and age on blood minerals, liver enzyme levels, and faecal egg counts in Nguni goats of South Africa

Gf¹,

Chimonyo²,

Dzama³

2012

Czech J. Anim. Sci.

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“…Young animals have relatively high levels of creatinine kinase which may be linked with susceptibility to stress-induced events such as capture and handling and capture myopathy [42]. Stress could affect transaminases activity in livestock animals [46]- [49], severe exercises (stressor) were reported to have resulted in an increase in these enzymes e.g. ALP and AST [50].…”

Section: The Influence Of Stress On Physiological Haematological Andmentioning

confidence: 99%

Parameters Influencing Haematological, Serum and Bio-Chemical References in Livestock Animals under Different Management Systems

Onasanya¹,

Oke²,

Sanni³

et al. 2015

OJVM

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Serum biochemical and haematological indices constitute important panels in the diagnosis, prognosis and treatment of livestock diseases via the investigations of myriads of parameters influencing these blood and serum biochemical indices. Serum biochemical indices, haematological indices and blood electrolytes are critical physiological indices which have health implications on the diagnosis, prognosis and treatment of livestock diseases especially in animals bred under different management systems. It is important to stress that cascades of parameters of both genetic and non-genetic origin greatly have direct and indirect health implications on serum biochemical indices and blood electrolytes in livestock animals and subsequently on their health/ production performances. Laboratory blood tests would be a vital tool to help detect any deviation from normal state of wellbeing in animals. Therefore, this review intends to provide base line information to establish certain haematological and serum biochemical indices as standard references which can be employed as alternative therapy for diagnosis, prognosis and treatment of cascades of diseases plaguing livestock animals bred under different management systems especially under the harsh condition of the tropics. Hence, it is important to establish standard values for the various blood and serum biochemical indices base on parameters of non-genetic origin; age, sex, physiological state, stress level, management systems, medication, health status, nutrition, hormone, climate, etc. and genetic parameters which include the breed and genotype of the animal among others obviously affect the blood and serum profile of healthy animal which subsequently influence their production performance and efficiency.

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“…The ALAT is a transaminase enzyme present in high concentrations in the cytoplasm of hepatocytes (Kupczynski and Chudoba-Drozdowska 2002). The ALAT is considered one of the most sensitive enzymes in the diagnosis of hepatocellular injury (Tibbo et al 2008). In our study, the values for the plasma concentrations of γ-GT and ALAT were close to the value ranges (20−50 IU/l for γ-GT and 15.3−52.3 IU/l for ALAT, respectively) of Tibbo et al (2008) and Djuricic et al (2011).…”

Section: Plasma Lipid Profile and Enzymatic Activitiesmentioning

confidence: 99%

Effect of hemp seed oil supplementation on plasma lipid profile, liver function, milk fatty acid, cholesterol, and vitamin A concentrations in Carpathian goats

Cozma¹,

Andrei²,

Pintea³

et al. 2015

Czech J. Anim. Sci.

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ABSTRACT:The aim of this study was to evaluate the effect of dietary supplementation with hemp seed oil (HSO) on the lipid metabolism, through the plasma lipid profile, liver function and concentrations of fatty acids (FA), cholesterol, and vitamin A in goat milk. Ten Carpathian goats were divided into two groups: one was fed the control diet (C) composed of alfalfa hay and concentrate, and the other was fed C diet supplemented with 93 g/day of HSO (4.7% of dry matter intake) for 31 days. The HSO supplementation did not modify plasma cholesterol, triglyceride or phospholipid concentrations, or the activities of alanine aminotransferase or γ-glutamyltransferase, but plasma total lipid concentration was increased. HSO supplementation had no effect on milk yield, but it increased milk fat and protein contents. HSO supplementation markedly altered milk FA composition, but had no effect on milk cholesterol or vitamin A concentrations. Changes in milk FA composition corresponded to a decrease in saturated de novo synthesized FA (10:0-16:0) and an increase in 4:0, 18:0, and polyunsaturated FA concentrations. Also, HSO supplementation strongly increased cis-9,trans-11-CLA and also trans-18:1 concentrations in milk fat. These findings suggest that HSO can be used to modify milk FA content with a putative positive effect on human health, without adversely affecting goat performance or health, except for a potential hyperlipidemic effect.

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Serum enzymes levels and influencing factors in three indigenous Ethiopian goat breeds

Cited by 28 publications

References 13 publications

Effect of season and age on blood minerals, liver enzyme levels, and faecal egg counts in Nguni goats of South Africa

Effect of season and age on blood minerals, liver enzyme levels, and faecal egg counts in Nguni goats of South Africa

Parameters Influencing Haematological, Serum and Bio-Chemical References in Livestock Animals under Different Management Systems

Effect of hemp seed oil supplementation on plasma lipid profile, liver function, milk fatty acid, cholesterol, and vitamin A concentrations in Carpathian goats

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