Serum levels of antioxidant vitamins, copper, zinc and magnesium in children with chronic rhinosinusitis

Ünal, Murat; Tamer, Lülüfer; Pata, Yavuz Selim; Kilic, Serkan; Degˇirmenci, Ulaş; Akbaş, Yücel; Görür, Kemal; Atik, Uğur

doi:10.1016/j.jtemb.2004.07.005

Cited by 33 publications

(27 citation statements)

References 19 publications

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“…Oxidative stress occurs when the overproduction of reactive oxygen species (ROS) such as hydroxyl radicals, superoxide anions, and hydrogen peroxide occurs [4] . Normally, the harmful effects of oxidation products are balanced by enzymatic and nonenzymatic antioxidation defense mechanisms.…”

Section: Introductionmentioning

confidence: 99%

“…Catalase, superoxide dismutase, and glutathione peroxidase are major enzymatic antioxidants, whereas ascorbic acid (Vitamin C), β-carotene (Vitamin A), α-tocopherol (Vitamin E), albumin, and uric acid are the major nonenzymatic antioxidants. Oxidative stress can cause severe tissue injury by provocating enzyme inactivation, lipid peroxidation, and deoxyribonucleic acid (DNA) damage [4] . Total antioxidant capacity (TAC) reflects the overall sum of the main antioxidants in the plasma and body fluids of human beings.…”

Section: Introductionmentioning

confidence: 99%

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The Role of Oxidative Stress and Inflammatory Mediators in Benign Paroxysmal Positional Vertigo

Gucluturk

Unal²,

İsmi³

et al. 2016

Int Adv Otol

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OBJECTIVE:Benign paroxysmal positional vertigo (BPPV) is the most common peripheral cause of vertigo. It can be defined as transient vertigo induced by rapid changes in head position associated with a characteristic paroxysmal positional nystagmus. The aim of this study was to search for the possible role of oxidative stress and inflammatory mediators in the pathogenesis of BPPV. MATERIALS and METHODS:Total antioxidant status as well as paraoxonase, tumor necrosis factor alpha, interleukin (IL) 6, and IL-1β levels were evaluated in peripheral venous serum samples of 30 BPPV and 30 control patients. RESULTS:Total antioxidant status levels were lower in the BPPV group than in the control group (p=0.008). After Epley's repositioning maneuver in the vertigo group, there was a statistically significant decline in IL-1β levels at the first and third month visits (p=0.014 for first month and p=0.013 for third month). CONCLUSION:Our findings suggested that IL-1β and oxidative stress contributed to the pathogenesis of BPPV.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Role of Oxidative Stress and Inflammatory Mediators in Benign Paroxysmal Positional Vertigo

Gucluturk

Unal²,

İsmi³

et al. 2016

Int Adv Otol

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show abstract

“…[12,15,16] There are also several studies exhibiting normal vitamin A levels and some others exhibiting low vitamin A levels. [11,12,15,16] Kompauer et al [17] showed low vitamin A level in the adults with AR. According to the literature search of the last ten years on children, there is no study on the relationship between AR and vitamin A level.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, vitamin A includes features such as anti-inflammatory, antiinfective and antioxidant effects. [11,12] As a consequence of increasing number of cells during the repair of damaged tissues and continuing inflammation, a lack of vitamin A may occur. [13] On respiratory syncytial virus and measles infections, there is evidence of lack of vitamin A.…”

Section: Discussionmentioning

confidence: 99%