Serum Levels of Zinc, Magnesium and Selenium among First Trimester Pregnant Saudi Women with Pre-Diabetes and Diabetes

Hammouda, Sahar A. Ibrahim; Sultan, Eman A.; Mohamadin, Ahmed M.

doi:10.4172/2161-1017.1000262

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…Hammouda and Mumena [37] and Kutbi et al [38] reported a positive correlation of A1C with TSH and HCY and a negative relation with vitamin B 12 , folate, and vitamin E, in the first-trimester-pregnant Saudi women, observations similar to ours. Along with this, a negative relation was also observed between A1C and minerals such as zinc and selenium in expectant mothers in their first trimester by Hammouda et al [39], also similar to our results. However, there was no information on their plastic usage frequency.…”

Section: Discussionsupporting

confidence: 93%

Use of Plastics with Hot Food among Saudi Pregnant Women Is Associated with Increased Concentrations of A1C, Thyroid-Stimulating Hormone, and Homocysteine and Decreased Concentrations of Vitamins and Minerals

2020

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Data regarding association between the use of plastics with hot food and levels of vitamins and minerals, and other biochemical parameters are lacking. Cross-sectional data for 740 healthy pregnant Saudi women were collected from 21 health care centres and 2 hospitals from Madinah, Saudi Arabia. Detailed data regarding the frequency of plastic use with hot food were collected, and laboratory analyses of thyroid-stimulating hormone (TSH), homocysteine (HCY), glycated A1C (A1C), and selected vitamins and minerals were also done. Daily use of plastics with hot food was frequently reported among young mothers (p = 0.002). Plastic use with hot food on a daily basis was positively associated with TSH, HCY, and A1C, while it was negatively associated with concentrations of vitamin E, zinc, and selenium. Future research should address the complex hormonal and metabolic abnormalities that are linked to the release of certain components associated with the use of plastics with hot food. Interventions are urgently needed to eliminate the use of plastics with hot food to prevent health complications that may result from the long-term use of these materials.

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Section: Discussionsupporting

confidence: 93%

Use of Plastics with Hot Food among Saudi Pregnant Women Is Associated with Increased Concentrations of A1C, Thyroid-Stimulating Hormone, and Homocysteine and Decreased Concentrations of Vitamins and Minerals

2020

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An observational study to estimate the level of essential trace elements and its implications in type 2 diabetes mellitus patients

Sonkar

Parmar

Ahmad

et al. 2021

Journal of Family Medicine and Primary Care

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Background and Objectives: Insulin action of reducing blood glucose has been found to be enhanced by trace elements. Material and Methods: This was a cross sectional study including 150 patients with Type 2 Diabetes Mellitus (T2DM) and 50 controls. Serum concentrations of zinc, copper, chromium, selenium and magnesium was measured by colorimetric kit. Fasting Blood Glucose and Glycated Haemoglobin (HbA1c) were assayed using the standard kit. Results: Out of 150 patients, 85.4% (n = 128) of the cases had uncontrolled blood sugar with HbA1c ≥7 and only 14.6% (n = 22) had good control of blood sugar with HbA1c <7%. Hypertension (42%) and hypothyroidism (14%) were the most commonly associated comorbidities among patients with T2DM. Following percentage of diabetic patients had complications such as peripheral neuropathy (45.3%), diabetic retinopathy (36.7%), coronary artery disease (20.7%), diabetic nephropathy (17.3%), peripheral vascular disease (8.7%), and cerebrovascular accident (6%) respectively. The mean level of zinc, copper, selenium and magnesium was significantly lower in patients with T2DM than the control cases (62.89 vs. 74.95 μg/dL, P < 0.05; 116.30 vs. 150.39 μg/dL, P < 0.001; 8.57 vs. 16.16 μg/dL, P < 0.001; 1.92 vs. 2.31 mg/dL, P < 0.05, respectively). Multivariate analysis showed that there was a significant trend between levels of zinc, copper, selenium, and magnesium and the prevalence of T2DM. Conclusions: The levels of selenium, zinc, copper, and magnesium were significantly lower in patients with T2DM when compared to healthy counterparts.

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Serum Levels of Zinc, Magnesium and Selenium among First Trimester Pregnant Saudi Women with Pre-Diabetes and Diabetes

Abstract: Background: Glycosylated hemoglobin (HbA1c) was found to be a valuable predictor of the risk of congenital malformations. Other studies documented diabetic complications in subjects with HbA1c at the pre-diabetic levels.

Cited by 2 publications

References 30 publications

Use of Plastics with Hot Food among Saudi Pregnant Women Is Associated with Increased Concentrations of A1C, Thyroid-Stimulating Hormone, and Homocysteine and Decreased Concentrations of Vitamins and Minerals

Use of Plastics with Hot Food among Saudi Pregnant Women Is Associated with Increased Concentrations of A1C, Thyroid-Stimulating Hormone, and Homocysteine and Decreased Concentrations of Vitamins and Minerals

An observational study to estimate the level of essential trace elements and its implications in type 2 diabetes mellitus patients

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