Serum lipid and apolipoprotein levels in a Nigerian population sample

Kesteloot, Hugo; Oviasu, V.O.; Obasohan, A. O.; Olomu, Adesuwa; Cobbaert, Christa; Lissens, W.

doi:10.1016/0021-9150(89)90156-1

Cited by 39 publications

(18 citation statements)

References 10 publications

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“…Other authors have documented similar results among hypertensive subjects and normotensive counterparts. 25 However, the proportion of smokers was statistically significantly higher among the hypertensive subjects. Comparing the hypertensive subjects with normal fasting glucose with those with impaired fasting glucose, the latter tended to have higher rates of hypertriglyceridaemia, hypo-HDL-cholesterolaemia, elevated LDL, hypercholesterolaemia and visceral obesity than those who had normal fasting glucose (Table II).…”

Section: Discussionmentioning

confidence: 83%

Epidemiology of conventional cardiovascular risk factors among hypertensive subjects with normal and impaired fasting glucose

Akintunde

2010

S Afr Med J

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Section: Discussionmentioning

confidence: 83%

Epidemiology of conventional cardiovascular risk factors among hypertensive subjects with normal and impaired fasting glucose

Akintunde

2010

S Afr Med J

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“…16 When compared with populations for which a similar methodology was used, median cholesterol levels were lower in the Seychelles (men, 5.0 and women, 5.4 mmol/1) than in most industrialized countries (e.g., California, 5.3 and 5.2; Finland, 6.2 and 6.2; Scotland, 6.2 and 6.4; Switzerland, 6.3 and 6.0 mmol/1) but higher than in Beijing (4.1 and 4.2 mmol/1). 14 The cholesterol values found in the Seychelles were higher than those observed in Nigeria and some other African countries 17 but were similar to those prevailing in black Americans. 18 In the Seychelles, fish and rice are part of almost every lunch and dinner.…”

Section: Discussionmentioning

confidence: 83%

High prevalence of cardiovascular risk factors in the Seychelles (Indian Ocean).

Bovet

Shamlaye

Kitua

et al. 1991

Arterioscler Thromb

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In recent years, increasingly high rates of cardiovascular diseases have been recorded in the Seychelles. A survey was performed to investigate the prevalence of cardiovascular risk factors in that population, which is shifting from its traditional habits to a westernized lifestyle. The Seychelles population is of predominantly black African origin. A sex-and age-stratified random sample of 1,309 subjects was drawn from 21,256 people aged 25-64 years. A response rate of 86% was achieved. The data showed a high prevalence of hypertension (25%) and cigarette smoking (54%) in men and a high prevalence of hypertension (20%) and obesity (21%) in women. Hypercholesterolemia (>6.5 mmol/1) was found in 9% of men and 15% of women. High density lipoprotein cholesterol levels (mean±SD) were higher in men (1.42±0.49 mmol/1) than in women (1J6±OJ4 mmol/1). High levels of lipoprotein (a) (mean±SD) were found both in men (319±362 ing/I) and women (328±415 mg/1). The high prevalence of cardiovascular risk factors identified in the Seychelles indicates a pressing current need for effective preventive strategies. (Arteriosclerosis and Thrombosis 1991;ll:1730-1736)

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“…1,26 Dyslipidemia has been reported to be lower among Black Africans than Caucasians. 27 The prevalence rate of obesity continues to increase worldwide which may lead to an increase in the prevalence rate of metabolic syndrome unless aggressive primary and secondary prevention strategies are implemented. The reported lower frequency of occurrence of metabolic syndrome among our study participants compared to Caucasians is suggested to be due to racial factors and possibly a lower prevalence of obesity and dyslipidemia among native Black Africans.…”

Section: Discussionmentioning

confidence: 99%

Metabolic Syndrome: Comparison of Occurrence Using Three Definitions in Hypertensive Patients

Akintunde¹,

Ayodele²,

Akinwusi³

et al. 2010

Clinical Medicine & Research

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Objective:To compare the frequency of occurrence of metabolic syndrome using three international definitions and to study the distribution of cardiovascular risk factors among newly diagnosed hypertensive Nigerian subjects.Design: Cross sectional study.Settings: Cardiology unit of LAUTECH Teaching Hospital, Osogbo, Nigeria. Participants:One hundred forty newly diagnosed hypertensive Nigerian subjects, and 70 normotensive controls (age-and sex-matched) were included in this study. Methods:Clinical history and relevant laboratory investigations were performed on all study participants. The definition of metabolic syndrome was based on three international definitions: World Health Organization (WHO), International Diabetes Federation (IDF), and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). Ethical approval was obtained for the study. Statistical analyses were performed using SPSS 16.0.Results: There was no difference in age and gender distribution between the hypertensive subjects and controls. (55.14 ± 10.83 years, females 53.6% vs. 54.67 ± 10.89 years, females 52.9% respectively, P>0.05). The frequency of occurrence of metabolic syndrome among hypertensives was 34.5% according to WHO, 35.0% according to NCEP ATP III, and 42.5% according to IDF criteria. Visceral obesity and reduced high-density lipoprotein (HDL) were the other common cardiovascular risk factors among newly diagnosed hypertensive subjects. Female hypertensives had a higher prevalence of visceral obesity and low HDL. Conclusion:Frequency of occurrence of metabolic syndrome was similar using the NCEP ATP III and WHO definitions. However, the IDF definition resulted in a higher frequency because of the lower cut-off for waist circumference used for identification of visceral obesity. Metabolic syndrome is present in a significant proportion of newly diagnosed hypertensive subjects. Therefore, appropriate screening and treatment are required.

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Serum lipid and apolipoprotein levels in a Nigerian population sample

Cited by 39 publications

References 10 publications

Epidemiology of conventional cardiovascular risk factors among hypertensive subjects with normal and impaired fasting glucose

Epidemiology of conventional cardiovascular risk factors among hypertensive subjects with normal and impaired fasting glucose

High prevalence of cardiovascular risk factors in the Seychelles (Indian Ocean).

Metabolic Syndrome: Comparison of Occurrence Using Three Definitions in Hypertensive Patients

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