Serum Uric Acid Level Increases in Proportion to the Severity of Pulmonary Thromboembolism.

Shimizu, Yuki; Nagaya, Noritoshi; Satoh, Tsuyoshi; Uematsu, Masaaki; Kyotani, Shingo; Sakamaki, Fumio; Nakanishi, Norifumi; Miyatake, Kunio

doi:10.1253/circj.66.571

Cited by 29 publications

(24 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Problems with sample handling and different assay characteristics for BNP and pro-BNP can alter measurements, and the absolute value has less significance than the trend. [138][139][140][141][142][143][144] As in adult PAH, increased levels of atrial natriuretic peptide, troponin T, 145 and uric acid 146,147 correlate with poor short-term outcome in older children and adolescents. …”

Section: Biomarkersmentioning

confidence: 99%

Pediatric Pulmonary Hypertension

Abman¹,

Hansmann²,

Archer³

et al. 2015

Circulation

948

405

View full text Add to dashboard Cite

Abstract-Pulmonary hypertension is associated with diverse cardiac, pulmonary, and systemic diseases in neonates, infants, and older children and contributes to significant morbidity and mortality. However, current approaches to caring for pediatric patients with pulmonary hypertension have been limited by the lack of consensus guidelines from experts in the field. In a joint effort from the American Heart Association and American Thoracic Society, a panel of experienced clinicians and clinician-scientists was assembled to review the current literature and to make recommendations on the diagnosis, evaluation, and treatment of pediatric pulmonary hypertension. This publication presents the results of extensive literature reviews, discussions, and formal scoring of recommendations for the care of children with pulmonary hypertension. Key Words: AHA Scientific Statements ◼ bronchopulmonary dysplasia ◼ congenital diaphragmatic hernia ◼ congenital heart disease ◼ genetics ◼ persistent pulmonary hypertension of the newborn ◼ sickle cell disease © 2015 by the American Heart Association, Inc., and the American Thoracic Society.Circulation is available at http://circ.ahajournals.org DOI: 10.1161/CIR.0000000000000329 †Deceased. The American Heart Association and the American Thoracic Society make every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This document was approved by the American Heart Association Science Advisory and Coordinating Committee on May 12, 2015, the American Heart Association Executive Committee on July 22, 2015, and the American Thoracic Society on July 24, 2015.The online-only Data Supplement is available with this article at http://circ.ahajournals.org/lookup/suppl/doi:10.1161/CIR.0000000000000329/-/DC1. The American Heart Association requests that this document be cited as follows: Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL; on behalf of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation, Council on Clinical Cardiology, Council on Cardiovascular Disease in the Young, Council on Cardiovascular Radiology and Intervention, Council on Cardiovascular Surgery and Anesthesia, and the American Thoracic Society. Pediatric pulmonary hypertension: guidelines from the American Heart Association and American Thoracic Society. Circulation. 2015;132:2037-2099 Copies: This document is available on the World Wide Web site of the American Heart Associat...

show abstract

Section: Biomarkersmentioning

confidence: 99%

Pediatric Pulmonary Hypertension

Abman¹,

Hansmann²,

Archer³

et al. 2015

Circulation

948

405

View full text Add to dashboard Cite

show abstract

“…A cascade of production or consumption and activation of different cellular mediatiors, cytokines eventually increase the superoxide radicals and intracellular calcium level. The enhanced leukocyte activation and the increased aggregation of thrombocytes disturb microcirculation causing tissue and cellular damage [23,[25][26][27][28][29][30].…”

Section: Discussionmentioning

confidence: 99%

“…Circulatory instability, hypoperfusion, hypoxia and ischaemia were found at the time of admission due to the pulmonary circulatory failure caused by massive PE which could be aggravated by OS [12].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of oxidative stress in the thrombolysis of pulmonary embolism

Mühl

Füredi

Cristofari

et al. 2006

J Thromb Thrombolysis

View full text Add to dashboard Cite

show abstract

“…[2][3][4][5] In this context, increased levels of uric acid are seen in respiratory disorders, including obstructive sleep apnoea 6 pulmonary thromboembolism. 7 There is data regarding the significance of serum uric acid level among patients with COPD. [8][9][10][11][12] Serum uric acid has been proposed as a marker of impaired oxidative metabolism and an independent prognostic marker in several cardio-vascular disorders such as congestive heart failure [13][14] pulmonary hypertension 15 and myocardial infarction and its related complications.…”

Section: Introductionmentioning

confidence: 99%

Correlation of serum uric acid levels in patients of chronic obstructive pulmonary disease

2020

PJMS

View full text Add to dashboard Cite

To evaluate serum uric acid level and correlate with the classification of chronic obstructive pulmonary disease (COPD) severity based on post-bronchodilator FEV1 as per Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. It is an institution based cross-sectional study in which 100 patients were included. Patients were screened for COPD. Clinical profile and oxygen saturation were included. Patients were classified according to GOLD guidelines. We found that serum uric acid level was at higher side in patients of severe and very severe stages of COPD compared to mild and moderate stages. Inverse relationship found between FEV1 and serum uric acid level. We concluded that uric acid is a widely available, easy to interpret, low cost biomarker, suggests the possible role in the identification of COPD patients of increased risk for adverse outcomes that may need early intensive management.

show abstract

Serum Uric Acid Level Increases in Proportion to the Severity of Pulmonary Thromboembolism.

Cited by 29 publications

References 35 publications

Pediatric Pulmonary Hypertension

Pediatric Pulmonary Hypertension

Evaluation of oxidative stress in the thrombolysis of pulmonary embolism

Correlation of serum uric acid levels in patients of chronic obstructive pulmonary disease

Contact Info

Product

Resources

About