Sesquiterpenes from the rhizome of Curcuma longa with inhibitory activity on superoxide generation and elastase release by neutrophils

Separation of an effective fraction from turmeric against Streptococcus mutans biofilms by the comparison of curcuminoid content and anti-acidogenic activity

“…Based on previous studies, the bio-activity of turmeric may be partially involved in sesquiterpenoids because these compounds, including ar-turmerone, are also major constituents of turmeric and have pharmacological activity (Chen et al, 2010). Moreover, sesquiterpenoids can disrupt the normal barrier function of the bacterial cell membrane due to their lipophilic properties, which is essential for bacterial growth and metabolic function (Brehm-Stecher & Johnson, 2003).…”

Curcuma longa L. 姜黄 (Jianghuang, Common Turmeric)

“…Twenty-eight sesquiterpenes, curculonone A, curculonone B, curculonone C, curculonone D, 6a-hydroxycurcumanolide A, 1,10-dehydro-10-deoxy-11-oxozedoarondiol, ar-turmerone (1), curlone, β-atlantone, zedoarondiol, curcumanolide A, and curcumanolide B, β-turmerone bisacumol, zingiberene, curcumenone, curcumenol, procurcumenol, dehydrocurdione and germacrone-13-al, (4S, 5S)-(+)-germacrone-4,5-epoxide, procurcumadiol, turmeronol A (2), turmeronol B (3), bisacurone (4), bisabola-3,10-dien-2-one, 4-hydroxybisabola-2,10-diene-11-one, 4-methoxy-5-hydroxy-bisabola-2,10-diene-11-one, 2,5-dihydroxybisabola-3,10-diene were isolated from C. longa [4,5].…”

Microwave-Assisted Extraction of Methyl β-Cyclodextrin-Complexed Curcumin from Turmeric Rhizome Oleoresin

“…Curcumin has been reported to possess hepatoprotective, antimicrobial wound healing, antitumor and antioxidative (Chen et al 2010), anti-inflammatory, antimutagenic, anticancer (Qureshi et al 1992), and hypoglycemic (Nishiyama et al 2005) activities. Despite all of therapeutic application of curcumin, its utility is limited due to poor water solubility and bioavailability and high decomposition rate (Anand 2008;Rajeswari et al 2005).…”