Sesquiterpenes produced by <i>Pestalotiopsis microspora</i> HF 12440 isolated from <i>Artocarpus heterophyllus</i>

Riga, Riga; Happyana, Nizar; Hakim, Euis H.

doi:10.1080/14786419.2019.1578764

Cited by 18 publications

(10 citation statements)

References 15 publications

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“…In India, it is also called “Panasa”, “Atibruhatphala”, “Kantaphal”, and “Kanthal” due to its physical characteristics. The AH tree is also considered to be a source of flavonoids, sterols, volatile acids, carotenoids, and tannins, which vary depending on the stage of maturity [ 6 , 7 , 8 , 9 , 10 ]. Moreover, it also has a unique combination of iron, vitamin C, vitamin B complex (especially vitamin B 6 , niacin, folic acid, and riboflavin), and minerals (mainly calcium and potassium) [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Gupta

Rather

Jha

et al. 2020

Plants

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Artocarpus heterophyllus Lam. (AH) and Artocarpus lakoocha Roxb. (AL) are two endemic plants that grow on the Asian continent. To date, their applications have been aimed at using their fruit as a food source or for some of their therapeutic virtues. In this study, attention was given to the flowers of AH and AL. Initially, the cytotoxicity of the phytoextracts was assessed, and the content of minerals, phenols, and flavonoids was determined. Furthermore, some antioxidant components were identified by HPLC. Furthermore, the ability of AH and AL extracts to modulate the gene expression of some targets involved in the antioxidant response was studied. The results obtained highlighted the nutritional and antioxidant value of the AH and AL flower extracts. This study will contribute to enhancing the use of AH and AL flowers as potential supplements in human nutrition.

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Section: Introductionmentioning

confidence: 99%

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Gupta

Rather

Jha

et al. 2020

Plants

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“…Cordyol C (126) was also a toxic compound against HeLa cells, with an IC 50 value of 35.29 ± 1.55 mM [99]. Sydowic acid (127) was assessed in murine leukemia P-388 cells and showed potential cytotoxicity, with an IC 50 value of 20.30 µg/mL [100]. Four secondary metabolites (128-131) (Figure 14) were isolated from the hydrothermal fungus Aspergillus sclerotiorum C10WU, which was collected from Kueishantao, Taiwan.…”

Section: Aspergillus Spmentioning

confidence: 99%

Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents

et al. 2022

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The deep sea has been proven to be a great treasure for structurally unique and biologically active natural products in the last two decades. Cold seeps and hydrothermal vents, as typical representatives of deep-sea extreme environments, have attracted more and more attention. This review mainly summarizes the natural products of marine animals, marine fungi, and marine bacteria derived from deep-sea cold seeps and hydrothermal vents as well as their biological activities. In general, there were 182 compounds reported, citing 132 references and covering the literature from the first report in 1984 up to March 2022. The sources of the compounds are represented by the genera Aspergillus sp., Penicillium sp., Streptomyces sp., and so on. It is worth mentioning that 90 of the 182 compounds are new and that almost 60% of the reported structures exhibited diverse bioactivities, which became attractive targets for relevant organic synthetic and biosynthetic studies.

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“…Akan tetapi, kajian aktivitas biologis dari ekstrak EtOAc jamur endofitik pada daun A. heterophyllus untuk pertama kalinya dipublikasikan pada kesempatan ini. Pelarut EtOAc digunakan pada penelitian karena bersifat semi polar sehingga dapat maksimal mengekstraksi metabolit sekunder yang terkandung dalam jamur endofitik (Riga et al, 2019b).…”

Section: Pembahasanunclassified

Aktivitas Sitotoksik dan Antibakteri Ekstrak Etil Asetat Jamur Endofitik Colletotrichum gloeosporioides

Riga¹,

Hakim²

2021

jfu

Self Cite

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Artocarpus heterophyllus merupakan salah satu tumbuhan yang dilaporkan menghasilkan beragam senyawa yang bersifat sitotoksik dan antibakteri. Selain melakukan studi kimia terhadap tumbuhan alaminya, eksplorasi terkait kajian fitokimia tumbuhan ini dapat dilakukan terhadap jamur endofitik yang berkolonisasi dengan tumbuhan A. heterophyllus. Tujuan penelitian ini adalah melakukan uji aktivitas antibakteri dan sitotoksik ekstrak EtOAC jamur endofitik yang berkolonisasi dengan daun A. heterophyllus. Tahapan dari penelitian ini terdiri dari inokulasi, sub-kultur, kultivasi jamur endofitik yang dilanjutkan dengan ekstraksi, uji aktivitas biologi dan uji kandungan kimia dari ekstrak etil asetat jamur Colletotrichum gloeosporioides yang diisolasi dari daun A. heterophyllus. Hasil uji sitotoksik menunjukkan bahwa ekstrak EtOAc jamur bersifat aktif terhadap sel murin leukemia P-388 dengan nilai IC50 18,97 µg/mL. Hasil uji antibakteri juga menunjukkan bahwa ekstrak EtOAc mempunyai kemampuan dalam menghambat pertumbuhan keempat bakteri uji dengan rentang zona hambat 4,3 – 14,3 mm. Untuk infomasi bagi kita semua bahwa penelitian terkait kajian sifat antibakteri dan sitotoksik dari jamur yang hidup pada daun A. heterophyllus baru pertama kali dilakukan pada kesempatan ini.

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Sesquiterpenes produced by Pestalotiopsis microspora HF 12440 isolated from Artocarpus heterophyllus

Cited by 18 publications

References 15 publications

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents

Aktivitas Sitotoksik dan Antibakteri Ekstrak Etil Asetat Jamur Endofitik Colletotrichum gloeosporioides

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