Seven‐year nationwide incidence of optic neuritis requiring intravenous methylprednisolone injection in Korean adults

Choi, Dai Hyuk; Park, Min‐Su; Park, Kyung‐Ah

doi:10.1111/aos.14326

Cited by 3 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, it has been abandoned due to the possibility of a serious complications, s u c h a s a c u t e p s y c h o s i s , a c u t e p a n c r e a t i t i s , a n d gastrointestinal bleeding, even in the treatment of spinal cord injury and brain injury. As the efficiency of intravenous methylprednisolone injection at a dose of 1,000 mg/d for 3 days has been evidenced in the treatment of optic neuritis, it was adopted in our center, with no apparent side effects (15).…”

Section: Discussionmentioning

confidence: 99%

The outcome of surgical and non-surgical treatments for traumatic optic neuropathy: a comparative study of 685 cases

Wang¹,

Zhao²,

Li³

et al. 2022

Ann Transl Med

View full text Add to dashboard Cite

Background: The choice and efficacy of surgical or/and surgical treatments for traumatic optic neuropathy (TON) remained controversial by now. This study aims to present the outcomes of surgical and nonsurgical treatments for TON in our center.Methods: A total of 685 consecutive patients were retrospectively included in the study. And divided into surgical and non-surgical groups. All cases were treated with corticosteroids for 3 days after admission.Endoscopic optic decompression was applied to 479 patients of surgical group; The other 206 patients of nonsurgical were administered with corticosteroids alone. The visual outcomes before and after treatment were compared with Wilcoxon rank and tests. The improvement rate between two groups were compared with chi-square test.Results: The visual acuity (VA) after treatment was significantly better than that before treatment (P=0.000).Overall VA improvement rate in the surgical group was better than that in non-surgical group (42.8% vs. 35.4%) with no significant difference (P=0.072). The VA improvement rate was significant greater in the surgical group than that in the non-surgical group in the patients with NLP before treatment (P=0.028). The VA improvement rate was better in the surgical group than that in the non-surgical group (71.9% vs. 57.8%) but with no significant difference. The final overall VA was 0.1 or better in 43 cases; 104 cases were able to count fingers; hand motion (HM) became perceivable in 132 cases; light perception (LP) was achieved in 53 cases; and no light perception (NLP) remained in 353 cases.Conclusions: Endoscopic optic nerve decompression (EOND) combined with corticosteroids or corticosteroids alone could reach the improvement for patients with TON. The EOND combined with corticosteroids could achieve better VA improvement in patients with NLP.

show abstract

Section: Discussionmentioning

confidence: 99%

The outcome of surgical and non-surgical treatments for traumatic optic neuropathy: a comparative study of 685 cases

Wang¹,

Zhao²,

Li³

et al. 2022

Ann Transl Med

View full text Add to dashboard Cite

show abstract

“…However, ON is less prevalent among children than it is among adults [ 2 ]. According to a population-based study, the annual incidence of ON among pediatric patients in South Korea is 1.04 per 100,000 people [ 3 ], which is less than that among adults (2.21–3.29 per 100,000) [ 4 , 5 ]. This is also slightly lower than the incidence of pediatric ON in Taiwan (1.79–2.46 per 100,000) [ 6 ] and higher than that in the US [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Optic Neuritis in South Korean Children and Adolescents: A Retrospective Multicenter Study

Park

Yang

Han

et al. 2022

Journal of Ophthalmology

Self Cite

View full text Add to dashboard Cite

Purpose. To analyze the clinical characteristics and prognosis of optic neuritis (ON) in pediatric patients aged <19 years in South Korea. Methods. This multicenter retrospective cohort study included 127 pediatric patients (median age: 10.3 (IQR: 7.3–14.2) years; female, 62.2%) who experienced ON for the first time between January 2004 and January 2018, with data obtained from five tertiary university-based hospitals in Korea. When ON was bilateral, the worse eye was selected for analysis. The baseline clinical characteristics and prognoses of patients, as well as the associations between these parameters, were analyzed. Results. The baseline clinical characteristics of the patients were as follows: best-corrected visual acuity (BCVA) < 20/200, 65.9%; pain on eye movement, 47.2%; optic disc swelling, 66.9%; and bilateral involvement, 41.7%. Among 101 patients who were followed up for ≥6 months, 48 (47.5%), 12 (11.9%), 19 (18.8%), 13 (12.9%), and 9 (8.9%) had been diagnosed with isolated ON, recurrent ON, multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and acute disseminated encephalomyelitis (ADEM)-related ON, respectively. At the latest visit, 81.9% and 71.1% had achieved BCVA of ≥20/40 and ≥ 20/25, respectively. Only disc swelling at presentation was associated with poor baseline BCVA (coefficient: 0.31, P = 0.004 ) and greater improvement in BCVA (coefficient: 0.49, P = 0.001 P = 0.001 ); there were no significant associations between the baseline factors and final BCVA. Conclusions. This study demonstrated pediatric ON-related clinical characteristics and visual outcomes in South Korea. Within this cohort, in about 40.6% of patients, ON was associated with other demyelinating diseases, namely, MS, NMOSD, and ADEM.

show abstract

Update on Optic Neuritis: An International View

Hickman

Petzold

2021

Neuro-Ophthalmology

View full text Add to dashboard Cite

Seven‐year nationwide incidence of optic neuritis requiring intravenous methylprednisolone injection in Korean adults

Cited by 3 publications

References 4 publications

The outcome of surgical and non-surgical treatments for traumatic optic neuropathy: a comparative study of 685 cases

The outcome of surgical and non-surgical treatments for traumatic optic neuropathy: a comparative study of 685 cases

Characteristics of Optic Neuritis in South Korean Children and Adolescents: A Retrospective Multicenter Study

Update on Optic Neuritis: An International View

Contact Info

Product

Resources

About