Sewing Hydrogels: Adhesion of Hydrogels Utilizing in Situ Polymerization of Linear Polymers inside Gel Networks

Abstract

Hydrogel materials attract much attention due to their high potential as artificial tissues including muscles and cartilages. For these applications, hydrogels must possess high mechanical strength, and adhesive systems for the adhesion of hydrogels to living tissues must be available. Recently, various hydrogels having high mechanical strength have been prepared by using organic structures or inorganic compounds. However, reports on adhesive systems for hydrogels that can be applied to practical use are still scarce. This paper describes the preparation of an adhesive hydrogel system, which can be used and applied easily, using in situ polymerization of linear polymers interpenetrated in the hydrogel networks. Additionally, this method allows to create a redox-responsive adhesive hydrogel system.

Programmed Multiresponsive Hydrogel Assemblies with Light‐Tunable Mechanical Properties, Actuation, and Fluorescence

“…The PAAm layer contained a dye (Me‐RDB) to enhance visibility and provide a positive charge to the surface which assisted electrostatic adhesion of the negatively charged MGs (see Figure S2C, Supporting Information). In contrast to other approaches for forming bilayers, the PRLDA method provided excellent adhesion without in situ free‐radical polymerization. At pH 7.4 the actuator was concave at all temperatures (Figure B, top row) due to high Q values for the MG gel layer (Figure A).…”

Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications

“…Earlier reports achieved this by diffusion and subsequent polymerization and cross-linking of monomer components. [73][74][75] Recent work by Tamesue et al 76 has extended this to temperature-and pH-responsive "thread" polymers, as well as application through oxidation-based polymerization, resulting in redox-responsive adhesion.…”

Effect of TEOA on the Process of Photopolymerization at 532 nm and Properties of Nanogels

“…6b, the FT‐IR absorption peak at 1415 cm ‐1 is attributed to the in‐plane scissoring vibration of =CH 2 acrylate end groups (58). The progress of PEGDA polymerization is confirmed by the gradual disappearance of the band attributed to the stretching vibration of the vinyl group at 1620 cm −1 (59). Double‐bond conversion α of the nanogels was calculated (Figure b), which based on the change in the integral area of the double bond before and after polymerization in the FT‐IR spectrum (Figure a).…”