Sexual dysfunction in multiple sclerosis: a 2-year follow-up study

Zorzon, Marino; Zivadinov, Robert; Bragadin, L. Monti; Moretti, Rita; Masi, Roberto De; Nasuelli, Davide; Cazzato, Giuseppe

doi:10.1016/s0022-510x(01)00493-2

Cited by 113 publications

(86 citation statements)

References 17 publications

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“…7,8 Untreated sexual dysfunction not only tends to worsen over time in the number and severity of symptoms but also can be detrimental to the mental health aspect of patients' health-related quality of life. [9][10][11] Treatment-wise, the current literature is sparse. That said, commonly used pharmaceutical treatments, such as phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil citrate), have been noted to have limited efficacy in the MS population.…”

Section: Methodsmentioning

confidence: 99%

Assessment and Treatment of Psychiatric Distress, Sexual Dysfunction, Sleep Disturbances, and Pain in Multiple Sclerosis

Gromisch¹,

Schairer²,

Pasternak³

et al. 2016

International Journal of MS Care

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Background: Psychiatric distress (depression and anxiety), sexual dysfunction, sleep disturbances, and pain are frequent comorbidities in multiple sclerosis (MS) that have the potential to interfere with functioning and quality of life. Often, patients benefit from a combination of medical and psychotherapeutic interventions. However, the literature suggests that many of these issues have been underdiagnosed or undertreated. To better understand current practices, this study aimed to gain a multidisciplinary perspective on how MS providers assess and treat these five problems.

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Section: Methodsmentioning

confidence: 99%

Assessment and Treatment of Psychiatric Distress, Sexual Dysfunction, Sleep Disturbances, and Pain in Multiple Sclerosis

Gromisch¹,

Schairer²,

Pasternak³

et al. 2016

International Journal of MS Care

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“…There is, as well, an association between the presence of sphinteric disorders and some symptoms of SD [47,48]. Relapse of the disease itself doesn't seem to add to the number of SD symptoms [49]. Most of the affected patients experience sexual hypoactivitiy [50].…”

Section: Sexual Dysfunctionmentioning

confidence: 99%

Autonomic dysfunction in multiple sclerosis

Adamec

Habek

2013

Clinical Neurology and Neurosurgery

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“…In the studies that investigated the relationship between SD and bladder/bowel symptoms, a relationship was found between SD and bladder problems (3,8,9). Minderhood (21) and Mattson (12) also detected an association between SD and bladder/bowel dysfunction in their studies.…”

Section: S Sd D ( (+ +) ) S Sd D ( (--mentioning

confidence: 99%

“…It may occur at any time during the course of MS and develops in more than half of the patients with MS (6,7). Long-term studies that evaluated the sexual functions of patients with MS are insufficient (4,8). There are several causes of SD in MS (9,10).…”

mentioning

confidence: 99%

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

Edemci¹,

Karakuş²,

Uçan³

et al. 2010

tftr

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S Su um mm ma ar ry y O Ob bj je ec ct ti iv ve e: : Sexual dysfunction (SD) is an important, but generally underestimated symptom in the course of multiple sclerosis (MS). The aim of this study was to investigate the factors related to SD in MS patients. M Ma at te er ri ia al ls s a an nd d M Me et th ho od ds s: : Twenty-one MS patients with and 21 MS patients without SD were included in this study. Age, SD duration, disease duration, marital status, educational status, bladder and bowel dysfunction, disability, independence, cognitive performances and psychological functioning and sexual function scales have also been assessed. R Re es su ul lt ts s: : SD correlated with age (p=0.029), disease duration (p=0.045), bladder dysfunction (X 2 =0.011; p=0.012). Positive correlations were found between disease duration and 5-point sexual function scale in SD patient (rs=0.419; p=0.027). However, SD did not correlated with bowel dysfunction (X 2 =0.469; p=0.418), disability (p=0.190), level of independence (p=0.146) and cognitive performances (p=0.212). The brain stem involvement was higher in patients with SD (X 2 =0.001; p=0.001). C Co on nc cl lu us si io on n: : The prevalence of SD increases with the patient age and prolonged disease duration. SD is related to bladder dysfunction and brain stem involvement. However, increased disability does not affect SD. Turk J Phys Med Rehab 2010;56:130-4. K Ke ey y W Wo or rd ds s: : Multiple sclerosis, sexual dysfunction Ö Öz ze et t A Am ma aç ç: : Seksüel disfonksiyon (SD), multipl skleroz (MS) seyri s›ras›nda görülen ancak genellikle gözard› edilen bir semptomdur. Bu çal›flman›n amac› MS'li hastalarda görülen SD ile iliflkili faktörlerin araflt›r›lmas›d›r. G Ge er re eç ç v ve e Y Yö ön nt te em m: : Çal›flmaya MS'ye ba¤l› SD'si bulunan 21 hasta ve bulunmayan 21 hasta dahil edildi. Yafl, SD süresi, hastal›k süresi, medeni durum, e¤itim durumu, mesane ve barsak disfonksiyonu varl›¤›, disabilite, konginitif performans, psikolojik fonksiyonlar ve seksüel durum de¤erlendirildi. B Bu ul lg gu ul la ar r: : SD varl›¤›; yafl, hastal›k süresi ve mesane disfonksiyonu varl›¤› ile koreleydi (s›ras›yla p=0,029, p=0,045, X 2 =0,011; p=0,012). Hastal›k süresi ve 5 puanl›k seksüel fonksiyon skalas› aras›nda, SD olan hastalarda pozitif korelasyon bulundu (rs=0,419; p=0,027). Buna ra¤men SD varl›¤› ile barsak disfonksiyonu varl›¤› (X 2 =0,469; p=0,418), disabilite düzeyi (p=0,190) ve kognitif performans (p=0,212) düzeyi korele bulunmad›. SD'lu hastalarda beyin sap› tutulumu daha yüksekti (X 2 =0,001; p=0,001). S So on nu uç ç: : SD s›kl›¤› hasta yafl› ve hastal›k süresi art›kça artmaktad›r. SD mesane disfonksiyonu ve beyin sap› tutulumu ile iliflkilidir. Ancak disabilite düzeyinin artmas› SD'nin görülme s›kl›¤›nda art›fla neden olmamaktad›r. Türk Fiz T›p Rehab Derg 2010;56:130-4. A An na ah ht ta ar r K Ke el li im me el le er r: : Multipl skleroz, seksüel disfonksiyon

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Sexual dysfunction in multiple sclerosis: a 2-year follow-up study

Cited by 113 publications

References 17 publications

Assessment and Treatment of Psychiatric Distress, Sexual Dysfunction, Sleep Disturbances, and Pain in Multiple Sclerosis

Assessment and Treatment of Psychiatric Distress, Sexual Dysfunction, Sleep Disturbances, and Pain in Multiple Sclerosis

Autonomic dysfunction in multiple sclerosis

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

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