In this work the texture evolution of a near β Ti-3Zr-2Sn-3Mo-25Nb (TLM) biomedical titanium alloy in hot compression at different deformation temperatures from 750°C to 850°C has been investigated. The XRD examination shows that the samples of hot deformation consist of β phase only. The development of texture has been explained in terms of orientation distribution functions (ODFs) of α and γ fibres. Compared with cold compression of TLM alloy, the texture changes obviously with the increase of deformation temperature. The {111}<110> texture shows the feature that weaken firstly and then strengthen, while the {111}<112> texture shows an opposite tendency. Specifically, the prominent texture components change to the {111}<110> and {111}<112> at the deformation temperature of 850°C, which are the same texture type and the nearly level of orientation density with the starting materials.