Shifting Host Choices of the Vector of Chagas Disease, Triatoma Infestans, in Relation to the Availability of Host in Houses in North-West Argentina

Gürtler, Ricardo E.; Cohen, Joel E.; Cecere, María C.; Chuit, Roberto

doi:10.2307/2404917

Cited by 82 publications

(98 citation statements)

References 25 publications

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“…The estimated density of infected bugs in each house was calculated as a weighted average by multiplying instar-specific infection prevalences and bug captures. The individual bloodmeals of domestic T. infestans were identified by agar doublediffusion tests using 5 family-specific anti-sera (human, dog, cat, chicken, and goat-sheep) (Gürtler et al 1997); of 1964 domestic T. infestans collected in Trinidad, Mercedes and Amamá from 1988 to 1992, 66% fed on humans, 45% on dogs, 27% on chickens, 11% on cats, and 2% on goat-sheep. The relation between bug infection with T. cruzi and type of host bloodmeal source in domestic T. infestans was analysed by the infective bloodmeal index defined by Zárate et al (1980) as the percentage of T. cruzi infected bugs among bugs with bloodmeals (both unmixed and mixed) on a given host.…”

Section: Entomological Surveymentioning

confidence: 99%

Domestic dogs and cats as sources ofTrypanosoma cruziinfection in rural northwestern Argentina

et al. 2006

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SUMMARYThe reservoir capacity of domestic cats and dogs for Trypanosoma cruzi infection and the hostfeeding patterns of domestic Triatoma infestans were assessed longitudinally in 2 infested rural villages in north-western Argentina. A total of 86 dogs and 38 cats was repeatedly examined for T. cruzi infection by serology and/or xenodiagnosis. The composite prevalence of infection in dogs (60%), but not in cats, increased significantly with age and with the domiciliary density of infected T. infestans. Dogs and cats had similarly high forces of infection, prevalence of infectious hosts (41-42%), and infectiousness to bugs at a wide range of infected bug densities. The infectiousness to bugs of seropositive dogs declined significantly with increasing dog age and was highly aggregated. Individual dog infectiousness to bugs was significantly autocorrelated over time. Domestic T. infestans fed on dogs showed higher infection prevalence (49%) than those fed on cats (39%), humans (38%) or chickens (29%) among 1085 bugs examined. The basic reproduction number of T. cruzi in dogs was at least 8·2. Both cats and dogs are epidemiologically important sources of infection for bugs and householders, dogs nearly 3 times more than cats.

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Section: Entomological Surveymentioning

confidence: 99%

Domestic dogs and cats as sources ofTrypanosoma cruziinfection in rural northwestern Argentina

et al. 2006

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“…Sylvatic and domestic animals play an important role in the life cycle of this parasite. Domestic dogs act maintaining the lifecycle of this parasite in the ambience, especially inside their dwellings, because those animals are a frequent source of blood meals for triatomines bugs (GÜRTLER et al, 1997(GÜRTLER et al, , 2007. In the State of Bahia, previous studies carried out in rural areas verified approximately 19.0% of dogs infected by T. cruzi -detected by xenodiagnosis (MOTT et al, 1978;BARRET et al, 1979).…”

Section: Introductionmentioning

confidence: 99%

First report of Trypanosoma cruziinfection in naturally infected dogs from southern Bahia, Brazil

Júnior

Almeida

Carvalho

et al. 2013

Rev. Bras. Parasitol. Vet.

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In order to verify the Trypanosoma cruzi infection in domestic domiciled dogs in a rural endemic area from the south region of the State of Bahia, Polymerase Chain Reaction (PCR) were performed using S35 and S36 primers in 272 dogs living in the district of Vila Operaria, in the municipality of Buerarema. All animals were clinically evaluated; 2.5 mL of blood were collected through venipuncture for the performance of molecular tests. None of these animals showed clinical signs of the illness and only two were identified with the DNA parasite. This result is the first report of natural infection by T. cruzi in domestic dogs in southern Bahia.Keywords: Trypanosoma cruzi, dog, PCR, Polymerase Chain Reaction, Bahia. ResumoCom o objetivo de verificar a infecção por Trypanosoma cruzi em cães domésticos domiciliados em área rural e endêmica do sul da Bahia, foi realizada a Reação em Cadeia da Polimerase (PCR), utilizando-se os iniciadores S35 e S36 em 272 cães domiciliados no distrito da Vila Operária, cidade de Buerarema. Todos os animais foram avaliados clinicamente e, posteriormente, foram coletados 2,5 mL de sangue por punção venosa para realização do diagnóstico molecular. Nenhum dos animais apresentou manifestação clínica da doença e, em apenas dois foram identificados DNA do parasito. Esse resultado é o primeiro relato de infecção natural por T. cruzi em cães domésticos no sul baiano.

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“…Natural infection by T. cruzi has been found in several local species of sylvatic mammals (Carcavallo and Martínez, 1968;Ceballos et al, 2006;Diosque et al, 2003;Yeo et al, 2005), whereas the putative sylvatic vectors have only been identified in Bolivia (Noireau et al, 2000). In the Gran Chaco, the bug Triatoma infestans is the main or single domiciliary vector; dogs, humans and chickens are usually the main blood meal sources of domestic bugs, and dogs and cats are considered the most important domestic reservoir hosts of T. cruzi (Minter, 1976;Gürtler et al, 1997Gürtler et al, , 2007a.…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina

Cardinal

Lauricella

Ceballos

et al. 2008

International Journal for Parasitology

111

108

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Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly endemic areas for Chagas disease, caused by T. cruzi. In this study we assessed the distribution of T. cruzi lineages (identified by PCR strategies) in Triatoma infestans, domestic dogs, cats, humans and sylvatic mammals from two neighboring rural areas with different histories of transmission and vector control in northern Argentina. Lineage II predominated among the 99 isolates characterized and lineage I among the six isolates obtained from sylvatic mammals. Trypanosoma cruzi lineage IIe predominated in domestic habitats; it was found in 87% of 54 isolates from Tr. infestans, in 82% of 33 isolates from dogs, and in the four cats found infected. Domestic and sylvatic cycles overlapped in the study area in the late 1980s, when intense domestic transmission occurred, and still overlap marginally. The introduction of T. cruzi from sylvatic into domestic habitats is likely to occur very rarely in the current epidemiological context. The household distribution of T. cruzi lineages showed that Tr. infestans, dogs and cats from a given house compound shared the same parasite lineage in most cases. Based on molecular evidence, this result lends further support to the importance of dogs and cats as domestic reservoir hosts of T. cruzi. We believe that in Argentina, this is the first time that lineage IIc has been isolated from naturally-infected domestic dogs and Tr. infestans.

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Shifting Host Choices of the Vector of Chagas Disease, Triatoma Infestans, in Relation to the Availability of Host in Houses in North-West Argentina

Cited by 82 publications

References 25 publications

Domestic dogs and cats as sources ofTrypanosoma cruziinfection in rural northwestern Argentina

Domestic dogs and cats as sources ofTrypanosoma cruziinfection in rural northwestern Argentina

First report of Trypanosoma cruziinfection in naturally infected dogs from southern Bahia, Brazil

Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina

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