Should children presenting with iron deficiency anaemia be screened for coeliac disease?

Winter, Sara; Halsey, Christina

doi:10.1136/archdischild-2013-305591

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…Recurrent or resistant iron deficient anaemia—Between 4.4% and 44% of patients present with iron deficiency alone, and it is present in up to 84% of patients with new coeliac disease 13. A smaller proportion of patients may experience anaemia secondary to folic acid malabsorption…”

Section: Why Is It Missed?mentioning

confidence: 99%

Coeliac disease in children

Thomas

Tighe

Beattie

2018

BMJ

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Section: Why Is It Missed?mentioning

confidence: 99%

Coeliac disease in children

Thomas

Tighe

Beattie

2018

BMJ

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“…It is important that any nutrient deficiencies (e.g. vitamin-D deficiency, iron-deficiency anaemia) detected at initial diagnosis are corrected 36,37 . Intestinal mucosa and tTG-titres will return to normal once GFD is initiated, this can however take up to a year depending on the initial level of tTG-titre 1 .…”

Section: Managementmentioning

confidence: 99%

Coeliac disease in children – an update for general dental practitioners

et al. 2016

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Coeliac disease (CD) is an immune-mediated systemic disorder caused by ingestion of gluten found in wheat, rye and barley. It affects around 1% of children but 90% of cases are considered to remain undiagnosed. CD classically presents with gastrointestinal manifestations including diarrhoea, bloating, weight loss and abdominal pain, but extra-intestinal features (including oral and dental manifestations) are increasingly being reported. Dental and oral manifestations such as dental enamel defects, delayed eruption of teeth, recurrent aphthous ulcers are well recognized manifestations of CD. In patients with yet undiagnosed CD, these can sometimes be the only presenting features. Dentists have regular contact with well children, and therefore the visit to the dentist is an opportunity to suspect CD. When CD is suspected, Dental practitioners can liaise with the General Medical Practitioner to organise screening for coeliac disease. Positive serology will prompt onward referral to a paediatric gastroenterologist to confirm the diagnosis. The recent European Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines have streamlined the diagnostic pathway for faster diagnosis of CD. Management involves strict adherence to a gluten free diet, which should lead to resolution of symptoms, recovery of intestinal mucosa and prevention of long-term complications associated with it. This article aims to describe CD, inform of recent changes to the diagnostic pathway and highlight the dental manifestations of the condition to equip Dental practitioners to aid early diagnosis and initiation of treatment for children with CD.

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“…But later studies showed that CD prevalence may higher in children with refractory IDA, as 44% (4,5). Winter et al (6) stated that CD diagnosis should be considered in every children with IDA, in particular those with recurrent IDA.…”

mentioning

confidence: 99%

Celiac disease and iron deficiency anemia

Gökçe

2015

Turk J Gastroenterol

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Should children presenting with iron deficiency anaemia be screened for coeliac disease?

Cited by 4 publications

References 15 publications

Coeliac disease in children

Coeliac disease in children

Coeliac disease in children – an update for general dental practitioners

Celiac disease and iron deficiency anemia

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