Simple and sensitive detection of acrylamide based on hemoglobin immobilization in carbon ionic liquid paste electrode

Li, Na; Liu, Xiaoying; Zhu, Jihe; Zhou, Bijing; Jing, Junxian; Wang, Aibing; Xu, Rui; Zhou, Wen; Shi, Xingbo; Guo, Shiyin

doi:10.1016/j.foodcont.2019.106764

Cited by 25 publications

(12 citation statements)

References 47 publications

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“…Recently, hemoglobin-modified electrodes have been developed for the detection of AM due to their adduct-forming ability with AM and thereby inhibiting electrochemical signature. Because of the impaired conductive nature of hemoglobin, electrode modifications using conductive materials such as multi-walled carbon nanotubes (MWCNTs) and ionic liquids have been attempted − Usually, a hemoglobin-modified electrode detects AM through formation of adduct Hb-Fe(II)-AM, and this leads to an increase of distance from the electrode surface. Consequently, a decline in peak current is observed, which is proportional to the AM concentration.…”

Section: Introductionmentioning

confidence: 99%

Poly(methylene blue)-Based Electrochemical Platform for Label-Free Sensing of Acrylamide

et al. 2021

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The present work reports the electrochemical sensing of acrylamide (AM) using a poly(methylene blue)-modified glassy carbon electrode (PMB/GCE) where PMB functions as an electrochemical reporter. PMB was prepared by electrochemical polymerization of methylene blue. Electrochemical sensing of AM was facilitated by the interaction between AM and PMB. Further the interaction between AM and PMB was investigated using ultraviolet–visible (UV–vis) spectroscopy and Raman analysis. The surface morphology was confirmed by atomic force microscopy (AFM) and field emission scanning electron microscopy (FESEM) analyses. PMB/GCE was further characterized by X-ray photoelectron spectroscopy (XPS), and the electrochemical performance was assessed using cyclic voltammetry and differential pulse voltammetry. Cyclic voltammetry analysis showed a decrease in current at the redox center of PMB upon addition of AM. The association constant and binding number of AM with PMB/GCE were calculated using differential pulse voltammetry and found to be 8.9 × 10 6 M –1 and 0.64 (∼1), respectively. The results indicated a strong interaction of AM on the PMB/GCE surface. Further, chronocoulometry analysis of PMB/GCE in the presence of AM showed a decrease in charge due to the interaction of AM with PMB. Under optimized conditions, PMB/GCE exhibited a decrease in current proportional to the concentration of AM in the range of 0.025–16 μM with sensitivity and detection limit 0.252 μA nM –1 and 0.13 nM, respectively. Real sample analysis was carried out by the standard addition method using the solution extracted from potato chips.

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Section: Introductionmentioning

confidence: 99%

Poly(methylene blue)-Based Electrochemical Platform for Label-Free Sensing of Acrylamide

et al. 2021

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“…That is why the Hb/CILPE must be used for direct electrochemical determination of acrylamide in food samples. [112] The molecularly imprinted technique is a good substitute for biomolecules recognition systems, including immunoreactions, enzyme-catalyzed reactions, aptamer, etc. For this, the IL 1-3vinyl imidazole bromide was prepared and used to invent a molecularly imprinted layer for making electrochemical sensing of Myo.…”

Section: Biosensormentioning

confidence: 99%

Ionic Liquid‐Based Polymer Nanocomposites for Sensors, Energy, Biomedicine, and Environmental Applications: Roadmap to the Future

et al. 2022

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Current interest toward ionic liquids (ILs) stems from some of their novel characteristics, like low vapor pressure, thermal stability, and nonflammability, integrated through high ionic conductivity and broad range of electrochemical strength. Nowadays, ionic liquids represent a new category of chemical‐based compounds for developing superior and multifunctional substances with potential in several fields. ILs can be used in solvents such as salt electrolyte and additional materials. By adding functional physiochemical characteristics, a variety of IL‐based electrolytes can also be used for energy storage purposes. It is hoped that the present review will supply guidance for future research focused on IL‐based polymer nanocomposites electrolytes for sensors, high performance, biomedicine, and environmental applications. Additionally, a comprehensive overview about the polymer‐based composites’ ILs components, including a classification of the types of polymer matrix available is provided in this review. More focus is placed upon ILs‐based polymeric nanocomposites used in multiple applications such as electrochemical biosensors, energy‐related materials, biomedicine, actuators, environmental, and the aviation and aerospace industries. At last, existing challenges and prospects in this field are discussed and concluding remarks are provided.

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“…Ionic liquids (IL), also called room temperature molten salts, are known for their versatile properties such as nonvolatility, predominant electrical and thermal conductivity, low melting point, high specific heat capacity and thermal stability, wider electrochemical windows, and also a green solvent as well . These make them quite attractive in the field of bioelectrochemistry, and based on this, Li et al had developed the first reported carbon ionic liquid paste electrode for AA detection . The electrode was made by mixing hydrophobic IL called 1-butyl-3 methyl-imidazolium hexafluorophosphate ([BMIM]PF6), which served as the binder and graphite powder as the conductive agent, respectively in a certain ratio.…”

Section: Recent Developmentsmentioning

confidence: 99%

“…Many of the reported sensors here have detection limits equal to and beyond the above-mentioned limits for these conventional methods. For example, sensors developed by Varmira et al, Li et al, Wulandari et al, Cheng et al, and Wang et al (refer to the respective materials of these sensors in Table ) are far more sensitive and have much lower detection limits than the above-mentioned limits for LC-MS and GC-MS methods. ,,,, Hence, these sensors have the potential to be scaled up for industrial monitoring of AA in food samples, particularly for point of detection analysis of processed food products at the production critical control points to strictly adhere to food quality control standards.…”

Section: Future Perspectivesmentioning

confidence: 99%

Nanomaterials Enabled and Bio/Chemical Analytical Sensors for Acrylamide Detection in Thermally Processed Foods: Advances and Outlook

Rayappa

Viswanathan

Rattu

et al. 2021

J. Agric. Food Chem.

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Acrylamide, a food processing contaminant with demonstrated genotoxicity, carcinogenicity, and reproductive toxicity, is largely present in numerous prominent and commonly consumed food products that are produced by thermal processing methods. Food regulatory bodies such as the U.S. Food and Drug Administration (U.S. FDA) and European Union Commission regulations have disseminated various acrylamide mitigation strategies in food processing practices. Hence, in the wake of such food and public health safety efforts, there is a rising demand for economic, rapid, and portable detection and quantification methods for these contaminants. Since conventional quantification techniques like liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS) methods are expensive and have many drawbacks, sensing platforms with various transduction systems have become an efficient alternative tool for quantifying various target molecules in a wide variety of food samples. Therefore, this present review discusses in detail the state of robust, nanomaterials-based and other bio/chemical sensor fabrication techniques, the sensing mechanism, and the selective qualitative and quantitative measurement of acrylamide in various food materials. The discussed sensors use analytical measurements ranging from diverse and disparate optical, electrochemical, as well as piezoelectric methods. Further, discussions about challenges and also the potential development of the lab-on-chip applications for acrylamide detection and quantification are entailed at the end of this review.

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Simple and sensitive detection of acrylamide based on hemoglobin immobilization in carbon ionic liquid paste electrode

Cited by 25 publications

References 47 publications

Poly(methylene blue)-Based Electrochemical Platform for Label-Free Sensing of Acrylamide

Poly(methylene blue)-Based Electrochemical Platform for Label-Free Sensing of Acrylamide

Ionic Liquid‐Based Polymer Nanocomposites for Sensors, Energy, Biomedicine, and Environmental Applications: Roadmap to the Future

Nanomaterials Enabled and Bio/Chemical Analytical Sensors for Acrylamide Detection in Thermally Processed Foods: Advances and Outlook

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