Simultaneous Determination of Antidepressants by Non-aqueous or Quasi-non-aqueous Capillary Electrophoresis

Sasajima, Yasuhide; Lim, Lee Wah; Takeuchi, Toyohide; Suenami, Koichi; Sato, Kiyohito; Takekoshi, Yuji

doi:10.2116/analsci.26.693

Cited by 8 publications

(8 citation statements)

References 27 publications

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“…Relative standard deviation (RSD) of migration times and peak areas are also shown in Table 2. Despite the aspiration effect, this system seemed to have almost the same error for the migration times and peak areas in comparison to those obtained by using the photodiode array detector [32]. The RSD of migration times when using internal standard indicated satisfactory values of less than 0.4%.…”

Section: Migration Time and Peak Area Optimization Using An Internal mentioning

confidence: 73%

“…At the concentration of treatment level, all of the antidepressants could be determined quantitatively except for setiptiline. It can be seen that the sensitivity achieved by TOF-MS is better than that of the photodiode array detector (DAD) [32] for the examined analytes.…”

Section: The Linearity Limits Of Detection (Lod) and Limits Of Quanmentioning

confidence: 94%

“…It can be seen from the figure that the resolution becomes poor with increasing water composition. Different organic solvents other than acetonitrile were not studied in the present work because acetonitrile achieved the best resolution among methanol, isopropanol and acetonitrile in the previous study [32]. The conductivity of the BGE increased with increasing water content in the BGE.…”

Section: Comparison Of Nace/ms and Aqueous Ce/msmentioning

confidence: 98%

“…NACE has been applied to various fields such as food chemistry, environmental chemistry, etc., nowadays [29]. For antidepressants, good results were obtained using NACE as described before [30][31][32]. The present NACE method can simultaneously determine more number of antidepressants than LC.…”

Section: Introductionmentioning

confidence: 98%

“…A photodiode array detector was previously used for studying the simultaneous determination of antidepressants by NACE method. As a result, 20 antidepressants could be analyzed at once [32]. However, a few issues still remained in the case of the photodiode array detector.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Simultaneous determination of antidepressants by non-aqueous capillary electrophoresis-time of flight mass spectrometry

Sasajima

Lim

Takeuchi

et al. 2010

Journal of Chromatography A

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Section: Migration Time and Peak Area Optimization Using An Internal mentioning

confidence: 73%

Section: The Linearity Limits Of Detection (Lod) and Limits Of Quanmentioning

confidence: 94%

Section: Comparison Of Nace/ms and Aqueous Ce/msmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Simultaneous determination of antidepressants by non-aqueous capillary electrophoresis-time of flight mass spectrometry

Sasajima

Lim

Takeuchi

et al. 2010

Journal of Chromatography A

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Enhanced chemiluminescence for trazodone trace analysis based on acidic permanganate oxidation in concurrent presence of rhodamine 6G

et al. 2017

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A new sensitized chemiluminescence method by acidic permanganate oxidation was developed for the sensitive determination of trazodone. A fluorescent dye as used rhodamine 6G to increase a chemiluminescence intensity. Under optimum conditions, the liner range of the calibration curve was obtained for 1-5000 nmol/L. The limit of detection was calculated from 3σ of a blank was 0.23 nmol/L. The coexistent ions and substances had no interference with the chemiluminescence measurement. The chemiluminescence spectra were measured to elucidate a possible mechanism for the system. The present method was satisfactorily used in the determination of the drugs in pharmaceutical samples and animal serums.

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A Novel Liquid–Liquid Extraction for the Determination of Sertraline in Tap Water and Waste Water at Trace Levels by GC–MS

Koçoğlu

Bakırdere

Keyf

2017

Bull Environ Contam Toxicol

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A simple, green and fast analytical method was developed for the determination of sertraline in tap and waste water samples at trace levels by using supportive liquid-liquid extraction with gas chromatography-mass spectrometry. Different parameters affecting extraction efficiency such as types and volumes of extraction and supporter solvents, extraction period, salt type and amount were optimized to get lower detection limits. Ethyl acetate was selected as optimum extraction solvent. In order to improve the precision, anthracene-D10 was used as an internal standard. The calibration plot of sertraline was linear from 1.0 to 1000 ng/mL with a correlation coefficient of 0.999. The limit of detection value under the optimum conditions was found to be 0.43 ng/mL. In real sample measurements, spiking experiments were performed to check the reliability of the method for these matrices. The spiking experiments yielded satisfactory recoveries of 91.19 ± 2.48%, 90.48 ± 5.19% and 95.46 ± 6.56% for 100, 250 and 500 ng/mL sertraline for tap water, and 85.80 ± 2.15% and 92.43 ± 4.02% for 250 and 500 ng/mL sertraline for waste water.

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Simultaneous Determination of Antidepressants by Non-aqueous or Quasi-non-aqueous Capillary Electrophoresis

Cited by 8 publications

References 27 publications

Simultaneous determination of antidepressants by non-aqueous capillary electrophoresis-time of flight mass spectrometry

Simultaneous determination of antidepressants by non-aqueous capillary electrophoresis-time of flight mass spectrometry

Enhanced chemiluminescence for trazodone trace analysis based on acidic permanganate oxidation in concurrent presence of rhodamine 6G

A Novel Liquid–Liquid Extraction for the Determination of Sertraline in Tap Water and Waste Water at Trace Levels by GC–MS

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