Simultaneous determination of microcystin contaminations in various vertebrates (fish, turtle, duck and water bird) from a large eutrophic Chinese lake, Lake Taihu, with toxic Microcystis blooms

Zhang, Dawen; Xie, Ping; Wang, Qing; Ma, Zhimei

doi:10.1016/j.scitotenv.2009.02.005

Cited by 134 publications

(79 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2). Bioaccumulation of MCs in zooplankton, shellfish, shrimps, fishes, frogs, and turtles have been documented [40][41][42][43][44]. Although there is no evidence for MCs biomagnification, the transfer of MCs within the aquatic food web takes place, suggesting that another route of exposure to the toxin, for aquatic species, is the consumption of aquatic organisms which have previously accumulated MCs in their tissues [44].…”

Section: Introductionmentioning

confidence: 99%

A review of reproductive toxicity of microcystins

Chen

Zhang

et al. 2016

Journal of Hazardous Materials

Self Cite

309

126

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

A review of reproductive toxicity of microcystins

Chen

Zhang

et al. 2016

Journal of Hazardous Materials

Self Cite

309

126

View full text Add to dashboard Cite

“…Since the world's first scientific report of poisoning livestock by toxic cyanobacteria in the nineteenth century (Francis 1878), there have been plenty of descriptions of fish, reptile, bird and mammal mortalities associated with exposure to cyanobacteria (Nasri et al 2008;Chen et al 2009;Carbis et al 1994). Some species of cyanobacteria can produce several toxic metabolites.…”

Section: Introductionmentioning

confidence: 99%

Why mammals more susceptible to the hepatotoxic microcystins than fish: evidences from plasma and albumin protein binding through equilibrium dialysis

Zhang

Gao

et al. 2013

Ecotoxicology

Self Cite

View full text Add to dashboard Cite

To elucidate the interspecies variation of susceptibility to microcystins (MCs), fresh plasma and purified albumin from six kinds of mammals and fish were used in toxins-substances binding test. Protein contents in the test plasma were analyzed and the binding characteristics to MCs were compared. Two kinds of widely observed MCs, microcystin-LR (MC-LR) and microcystin-RR (MC-RR) were tested and data were collected through the method of equilibrium dialysis. It was found that total plasma protein and albumin content in mammals were nearly two times and four times higher than that in fish, respectively. In the test range of 0-100 lg/mL, binding rates of fish plasma to MCs were considered significant lower (p \ 0.01) than that of mammals. And human plasma demonstrated the highest binding rate in mammals. In all the test species, plasma protein binding rates of MC-RR were significantly higher than MC-LR (p \ 0.01). Besides, binding profiles of albumin were acquired under the protein content of 0.67 mg/mL. Human serum albumin demonstrated the highest affinity to MCs throughout the six species and differences among the other five species were considered not significant (p [ 0.05). From the view of protein binding, it is concluded that both the variation of plasma protein composition and albumin binding characteristic could influence the existing form of MCs in circulation, change MCs utilization, alter MCs half-life and further contribute to the difference of susceptibility between mammals and fish.

show abstract

“…In post-blooms, MCs are released into water after demise of Microcystis cells. The dissolved MCs > 1800 mg.L x1 during the collapse of heavy blooms (Jones and Orr, 1994;Svrcek and Smith, 2004) can come in contact with a wide range of aquatic organisms including rotifers and have adverse effects on them , 2009a, Cazenave et al, 2006. MCs including MC-LR inhibit feeding, reduce growth, and increase mortality in cladocerans (DeMott et al, 1991; Rohrlack …”

Section: Discussionmentioning

confidence: 99%

“…It is well known that many species of cyanobacteria are able to produce microcystins (MCs) (van Apeldoorn et al, 2007), which can accumulate in the food chain (Xie et al, 2005;Chen et al, 2009a) and negatively affect aquatic organisms, animals, and human beings due to their potent hepatotoxicity and probable tumor promoters (Andersen et al, 1993;Carmichael and Falconer, 1993;Chorus and Bartram, 1999;Matsunaga et al, 1999;Carmichael et al, 2001;Zimba et al, 2001;Chen et al, 2002Chen et al, , 2009bQiu et al, 2007). To date, more than 80 structural analogues of MCs have been identified, and microcystin-LR (MC-LR) is the most frequently detected and the most toxic (Fastner et al, 2002;Briand et al, 2003;Zurawell et al, 2004;Hoeger et al, 2005;Blaha et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Responses in population growth and reproduction of the freshwater rotiferBrachionus calyciflorusto microcystin-LR at different temperatures

Huang

et al. 2012

Ann. Limnol. - Int. J. Lim.

View full text Add to dashboard Cite

-Microcystis blooms occur worldwide in eutrophic lakes. Microcystins (MCs) including microcystin-LR (MC-LR) released by Microcystis have adverse effects on aquatic organisms such as rotifers. To detect population growth and reproductive responses, the rotifer Brachionus calyciflorus was exposed to MC-LR at eight concentrations ranging from 0 to 200 mg.L x1 under different temperature (20, 25 and 30 xC), and population growth rate (r), ovigerous females/non-ovigerous females (OF/NOF) ratio, mictic females/amictic females (MF/AF) ratio, mictic rate (MR), and 7-d resting egg (7-d RE) production were investigated. The results showed that higher temperatures stimulate the population growth of B. calyciflorus. B. calyciflorus showed high tolerance to MC-LR at concentrations lower than 200 mg.L x1 under different temperatures. Compared to the control, MC-LR at all concentrations increased the r (P < 0.05), but decreased the OF/NOF and the MR of the rotifers at 30 xC (P < 0.01). A clear dose-response relationship existed between the r, the OF/NOF, and the MR of B. calyciflorus and MC-LR concentration at 30 xC, respectively. These sensitive parameters could be used to monitor the ecological effects of low concentrations of MC-LR in natural water bodies at the high temperature.

show abstract

Simultaneous determination of microcystin contaminations in various vertebrates (fish, turtle, duck and water bird) from a large eutrophic Chinese lake, Lake Taihu, with toxic Microcystis blooms

Cited by 134 publications

References 35 publications

A review of reproductive toxicity of microcystins

A review of reproductive toxicity of microcystins

Why mammals more susceptible to the hepatotoxic microcystins than fish: evidences from plasma and albumin protein binding through equilibrium dialysis

Responses in population growth and reproduction of the freshwater rotiferBrachionus calyciflorusto microcystin-LR at different temperatures

Contact Info

Product

Resources

About