Simultaneous determination of multi-class antibiotic residues in water using carrier-mediated hollow-fiber liquid-phase microextraction coupled with ultra-high performance liquid chromatography tandem mass spectrometry

Yudthavorasit, Soparat; Chiaochan, Chayada; Leepipatpiboon, Natchanun

doi:10.1007/s00604-010-0454-6

Cited by 58 publications

(23 citation statements)

References 33 publications

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“…MDL and MQL values ranged from 0.7 to 3 ng/L and from 2.4 to 10 ng/L, respectively. These values are considered reliable, according to other methods developed for the same purpose (Batt and Aga, 2005;Himmelsbach and Buchberger, 2005;Choi et al, 2007;Ye et al, 2007;Luo et al, 2010;Payán et al, 2011;Rodríguez et al, 2011;Gros et al, 2013;Zhou et al, 2012;Yudthavorasit et al, 2010). Matrix effects were accessed comparing recoveries in spiked Milli-Q water and spiked samples (n = 3).…”

Section: Validation Resultsmentioning

confidence: 99%

Fluoroquinolones and Tetracycline Antibiotics in a Portuguese Aquaculture System and Aquatic Surroundings: Occurrence and Environmental Impact

Pereira

Silva

Meisel

et al. 2015

Journal of Toxicology and Environmental Health, Part A

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The growth of aquaculture over the past few years is widely recognized as one of the main sources of antibiotics, mainly fluoroquinolones (FQ) and tetracyclines (TC), in the aquatic environment, consequently, increasing the risk of the emergence of antibiotic bacterial resistance and promoting the spread of resistant genes. This study aimed to (1) develop and validate a multiresidue method for determination and quantification of ciprofloxacin (CIP), difloxacin (DIFL), enrofloxacin (ENR), norfloxacin (NOR), sarafloxacin (SARA), and oxytetracycline (OXY) in aquaculture waters and surrounding water bodies and (2) provide the first Portuguese data to utilize in assessment of risk of adverse effects. In addition, the potential environmental impact posed by these antibiotics to aquatic organisms, belonging to different trophic levels, when exposed to the studied aquaculture waters was also assessed. The analytical strategy comprised of solid-phase extraction (SPE) through Oasis HLB cartridges, and detection and quantification by liquid chromatography with tandem mass spectrometry (LC/MS(n)). Method detection limits (MDL) and method quantification limits (MQL) were in the range of 0.7-3 ng/L and 2.4-10 ng/L, respectively. Recoveries varied between 57.4 and 122.8%. The method was applied to 31 water samples collected from an aquaculture and surrounding water bodies located in north of Portugal. Residues of all antibiotics, except SARA and DIFL, were detected at concentrations ranging from 3 to 75.1 ng/L. Norfloxacin was the antibiotic present at highest frequency and concentration. Regarding the environmental impact assessment (EIA), a risk quotient higher than 1 was observed for NOR.

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Section: Validation Resultsmentioning

confidence: 99%

Fluoroquinolones and Tetracycline Antibiotics in a Portuguese Aquaculture System and Aquatic Surroundings: Occurrence and Environmental Impact

Pereira

Silva

Meisel

et al. 2015

Journal of Toxicology and Environmental Health, Part A

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“…Several LPME methods have been developed and successfully applied for the determination of sulfonamides in water samples [17,21,22]. All the currently proposed methods are based on three-phase HF-LPME [17,21] or carrier-LPME [22] modes using a tenuous hollow fiber.…”

Section: Introductionmentioning

confidence: 99%

“…All the currently proposed methods are based on three-phase HF-LPME [17,21] or carrier-LPME [22] modes using a tenuous hollow fiber. The above three-phase LPME suffers from strict pH control of both the sample and acceptor solutions, which makes the operation more complex than two-phase LPME.…”

Section: Introductionmentioning

confidence: 99%

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Ionic liquid‐based single‐drop liquid‐phase microextraction combined with high‐performance liquid chromatography for the determination of sulfonamides in environmental water

Guo

Yin

Peng

et al. 2012

J of Separation Science

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A simple, rapid and environment-friendly technique of single-drop liquid-phase microextraction has been developed for the determination of sulfonamides in environmental water. Several important parameters including stirring rate, extraction solvent, extraction pH, salinity and extraction time were optimized to maximize the extract efficiency. Extraction solvent 1-octyl-3-methylimidazolium hexafluorophosphate [C(8) MIM][PF(6) ] ionic liquid showed better extraction efficiency than 1-butyl-3-methylimidazolium hexafluorophosphate [C(4) MIM][PF(6) ] and 1-octanol. The optimum experimental conditions were: pH, 4.5; sodium chloride content, 36% w/v; extraction time, 20 min. This method provided low detection limits (0.5-1 ng/mL), good repeatability (the RSD ranging from 4.2 to 9.9%, n=5) and wide linear range (1-1500 ng/mL), with determination coefficients (r(2) ) higher than 0.9989 for all the target compounds. Real sample analysis showed relative recoveries between 63.5 and 115.8% for all the target compounds.

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“…High selectivity with these membranes can be achieved by the selection of suitable complexing agents or ion-exchangers as carriers. As an example, three-phase hollow fiber liquid phase microextraction (HF-LPME), a class of SLM-based techniques, has been successfully applied for the determination of antibiotics in water samples [14,15].…”

Section: Introductionmentioning

confidence: 99%

Development of a polymer inclusion membrane (PIM) for the preconcentration of antibiotics in environmental water samples

Garcia-Rodríguez

Matamoros

Kolev

et al. 2015

Journal of Membrane Science

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Simultaneous determination of multi-class antibiotic residues in water using carrier-mediated hollow-fiber liquid-phase microextraction coupled with ultra-high performance liquid chromatography tandem mass spectrometry

Cited by 58 publications

References 33 publications

Fluoroquinolones and Tetracycline Antibiotics in a Portuguese Aquaculture System and Aquatic Surroundings: Occurrence and Environmental Impact

Fluoroquinolones and Tetracycline Antibiotics in a Portuguese Aquaculture System and Aquatic Surroundings: Occurrence and Environmental Impact

Ionic liquid‐based single‐drop liquid‐phase microextraction combined with high‐performance liquid chromatography for the determination of sulfonamides in environmental water

Development of a polymer inclusion membrane (PIM) for the preconcentration of antibiotics in environmental water samples

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