Simultaneous electrochemical recognition of tryptophan and penicillamine enantiomers based on MOF-modified β-CD

Recent advances in β-cyclodextrin-based materials for chiral recognition

“…Once a water-soluble macrocyclic host such as b-CD is introduced into graphene, the dispersion ability and enantiomeric recognition of b-CD-modified graphene are improved. 31 Therefore, a reasonable combination of graphene and b-CD has a possibility to create some advanced chiral sensors (Table 1).…”

An electrochemical chiral sensor based on competitive host–guest interaction for the discrimination of electroinactive amino acids

“…12 It has been used in chiral discrimination because it can form inclusion complexes with guest molecules and display different association constants with the isomers of chiral guest molecules. [13][14][15] Since β-CD is a kind of electroinactive polysaccharide, electroactive signal probes are necessary for β-CD-based chiral electroanalysis. The commonly used electroactive probes can be divided into two categories: organic dyes and organometallic complexes.…”

Chiral Discrimination of Penicillamine Enantiomers: The Role of Aggregation-Caused Quenching in Achieving High Selectivity

“…This approach is recommended for the first time for selective recognition of penicillamine (PA) enantiomers, which are penicillin metabolites with varied pharmacological activities or toxicities in living organisms. d -PA is useful in treating heavy metal poisoning, Wilson’s disease, and rheumatoid arthritis, while L-PA can cause unpleasant side effects such as neuritis, osteomyelitis, and degeneration of olfactory vision in humans. – …”