Simultaneous voltammetric detection of anti-depressant drug, sertraline HCl and paracetamol in biological fluid at CNT-cesium modified electrode in micellar media

Detection and Treatment of Persistent Pollutants in Water: General Review of Pharmaceutical Products

“…Additionally, the redox processes tend to be irreversible. [10,39,48,49] These drawbacks can be minimized by modifying the surface of the electrodes with conductive or semiconductor materials. Senson surface treating is an area of interest for various interdisciplinary research groups, ranging from the synthesis and characterization of materials, their use as sensors and finally their application in the determination of PPs in samples that can be from biological, food and environmental sources.…”

“…This electrode preparation is simple and the LOD is good, on the order of nM (9.2 nM), despite the presence of interfering drugs, the sensor showed good selectivity to the antidepressant. [49] Other novel studies are based on sensors with a more robust composition including a GCE modified with a Ni(II)-LevodopaNSs/AuNPs/MWCNT composite nanostructure prepared by an electrodeposition processes. [10] The electrode has excellent stability since 80 % of the initial current response is retained after 4 weeks of storage at room temperature.…”

“…There is evidence that when conventional (bare) electrodes are used to perform the determination, the oxidation process requires high potentials (overpotentials) which negatively influences the detection sensitivity. Additionally, the redox processes tend to be irreversible [10,39,48,49] . These drawbacks can be minimized by modifying the surface of the electrodes with conductive or semiconductor materials.…”

“…There are novel proposals, such as a modified CPE with MWCNT/cesium in molecular media, where only a mixture made up of each of the components is prepared to coat the electrode. This electrode preparation is simple and the LOD is good, on the order of nM (9.2 nM), despite the presence of interfering drugs, the sensor showed good selectivity to the antidepressant [49] . Other novel studies are based on sensors with a more robust composition including a GCE modified with a Ni(II)‐LevodopaNSs/AuNPs/MWCNT composite nanostructure prepared by an electrodeposition processes [10] …”

Development and Validation of an RP-HPLC-PDA Method for Determination of Paracetamol, Caffeine and Tramadol Hydrochloride in Pharmaceutical Formulations

“…Similarly, the same three analytes, together with other compounds, have been determined by desorption electrospray ionization–mass spectrometry (DESI–MS) [ 32 ]. Nonetheless, additional analytical instrumentation based on cyclic voltammetry has also provided successful procedures for the determination of paracetamol [ 35 , 36 ], and paracetamol and caffeine [ 37 ] and paracetamol, caffeine and tramadol [ 38 ] in solid formulations.…”