Site-selective immobilization of functionalized DNA origami on nanopatterned Teflon AF

Shaali, Mehrnaz; Woller, Jakob G.; Johansson, Peter; Hannestad, Jonas K.; Battice, Laura De; Aissaoui, Nesrine; Brown, Tom; El‐Sagheer, Afaf H.; Kubatkin, Sergey; Lara‐Avila, Samuel; Albinsson, Bo; Jesorka, Aldo

doi:10.1039/c7tc01015j

Cited by 7 publications

(13 citation statements)

References 36 publications

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“…[54] Such assemblies can be achieved through patterning the substrate to immobilize the DNA-origami nanostructures. [55][56][57] We therefore think that our mold-based platform for the fabrication of metal nanoparticles with programmable shape will be a promising tool to realize different applications in nanoelectronics and nanooptics.…”

Section: Discussionmentioning

confidence: 99%

Complex Metal Nanostructures with Programmable Shapes from Simple DNA Building Blocks

Aftenieva

Bayrak

et al. 2021

Advanced Materials

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Advances in DNA nanotechnology allow the design and fabrication of highly complex DNA structures, uisng specific programmable interactions between smaller nucleic acid building blocks. To convey this concept to the fabrication of metallic nanoparticles, an assembly platform is developed based on a few basic DNA structures that can serve as molds. Programming specific interactions between these elements allows the assembly of mold superstructures with a range of different geometries. Subsequent seeded growth of gold within the mold cavities enables the synthesis of complex metal structures including tightly DNA‐caged particles, rolling‐pin‐ and dumbbell‐shaped particles, as well as T‐shaped and loop particles with high continuity. The method further supports the formation of higher‐order assemblies of the obtained metal geometries. Based on electrical and optical characterizations, it is expected that the developed platform is a valuable tool for a self‐assembly‐based fabrication of nanoelectronic and nanooptic devices.

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Section: Discussionmentioning

confidence: 99%

Complex Metal Nanostructures with Programmable Shapes from Simple DNA Building Blocks

Aftenieva

Bayrak

et al. 2021

Advanced Materials

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“…Yun et al [ 139 ] presented attachment of rectangular DNA origami on various types of patterned graphene oxide surfaces, in the presence of divalent Mg 2+ bridging the structure and surface. Hydrophobic interactions have also been used to immobilize rectangular DNA origami on Teflon amorphous fluoropolymer (Teflon AF) [ 140 ]. In the study, porphyrin was conjugated to the origami structure to mediate the binding to hydrophobic Teflon forming square lattice with a minimum feature size of 40 nm and 1 µm pitch ( Figure 7 c).…”

Section: Surface-assisted Assemblymentioning

confidence: 99%

“…Adapted from Ref. [ 140 ] with permission from The Royal Society of Chemistry. ( d ) AFM image of DNA origami tubes with thiol-modified ends connecting a hexagonal gold lattice; scale bar 500 nm [ 95 ].…”

Section: Figurementioning

confidence: 99%

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Constructing Large 2D Lattices Out of DNA-Tiles

et al. 2021

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The predictable nature of deoxyribonucleic acid (DNA) interactions enables assembly of DNA into almost any arbitrary shape with programmable features of nanometer precision. The recent progress of DNA nanotechnology has allowed production of an even wider gamut of possible shapes with high-yield and error-free assembly processes. Most of these structures are, however, limited in size to a nanometer scale. To overcome this limitation, a plethora of studies has been carried out to form larger structures using DNA assemblies as building blocks or tiles. Therefore, DNA tiles have become one of the most widely used building blocks for engineering large, intricate structures with nanometer precision. To create even larger assemblies with highly organized patterns, scientists have developed a variety of structural design principles and assembly methods. This review first summarizes currently available DNA tile toolboxes and the basic principles of lattice formation and hierarchical self-assembly using DNA tiles. Special emphasis is given to the forces involved in the assembly process in liquid-liquid and at solid-liquid interfaces, and how to master them to reach the optimum balance between the involved interactions for successful self-assembly. In addition, we focus on the recent approaches that have shown great potential for the controlled immobilization and positioning of DNA nanostructures on different surfaces. The ability to position DNA objects in a controllable manner on technologically relevant surfaces is one step forward towards the integration of DNA-based materials into nanoelectronic and sensor devices.

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“…The combination of bottom-up self-assembly and top-down lithography for providing precise locations for DNA on a surface is also a useful strategy. Shaali et al [ 72 ] performed deposition of DNA origami modified by hydrophobic anchors with surface coverage of ~80% of sites in a Teflon negative electron beam (e-beam) resist pattern. Figure 2 b shows a schematic of the nanopattern designed to localize DNA structures and an AFM image of the surface after e-beam exposure and development of a 35 nm Teflon resist.…”

Section: Metallization Of Dna Templatesmentioning

confidence: 99%

Bottom-Up Fabrication of DNA-Templated Electronic Nanomaterials and Their Characterization

et al. 2021

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Bottom-up fabrication using DNA is a promising approach for the creation of nanoarchitectures. Accordingly, nanomaterials with specific electronic, photonic, or other functions are precisely and programmably positioned on DNA nanostructures from a disordered collection of smaller parts. These self-assembled structures offer significant potential in many domains such as sensing, drug delivery, and electronic device manufacturing. This review describes recent progress in organizing nanoscale morphologies of metals, semiconductors, and carbon nanotubes using DNA templates. We describe common substrates, DNA templates, seeding, plating, nanomaterial placement, and methods for structural and electrical characterization. Finally, our outlook for DNA-enabled bottom-up nanofabrication of materials is presented.

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Site-selective immobilization of functionalized DNA origami on nanopatterned Teflon AF

Abstract: Teflon AF acts as a negative e-beam resist, here utilized for immobilization of porphyrin-anchored single DNA molecules on nanopillars, and precise determination of individual label positions.

Cited by 7 publications

References 36 publications

Complex Metal Nanostructures with Programmable Shapes from Simple DNA Building Blocks

Complex Metal Nanostructures with Programmable Shapes from Simple DNA Building Blocks

Constructing Large 2D Lattices Out of DNA-Tiles

Bottom-Up Fabrication of DNA-Templated Electronic Nanomaterials and Their Characterization

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