Menopause is an age-related factor that profoundly alters the structures and quality of the skin. In this study, researchers tested the oral supplementation of organic silicon (200mg) and topical use of silicon (5%).Three post-menopausal women were recruited and divided into three groups: oral use, topical use, and oral and topical use. The treatment lasted for 30 days. Ultrasound imaging tests were performed to assess dermal thickness of the skin in four distinct regions of the face. After 30 days of treatment, was observed an improvement in the dermal thickness in the three treatments, but the most expressive results was observed in the woman who used oral and topical use. Thus, the association of organic silicon may be promising in improving skin quality associated with menopause.