2014
DOI: 10.1016/j.pcl.2014.08.001
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Slipped Capital Femoral Epiphysis

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Cited by 55 publications
(62 citation statements)
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“…Since the perichondral ring is thin, the wide surface area of the undulating, interlocking mammillary processes guarantee most of the internal support of the normal physis. On the other hand, SCFE is characterized by physeal widening (as much as 12 mm, with normal range 2–6 mm), a widened hypertrophic zone comprising 60%–80% of physeal height, enlargement of chondrocytes, cellular column disorganization, higher proteo-glycan and extracellular matrix concentrations in the physis, and widespread disruption in chondrocyte differentiation and endochondral ossification 8. Radiographic physeal widening underlines a mechanically weakening of the physis that is susceptible to unlocking mammillary processes, resulting in further destabilization.…”
Section: Etiology and Histopathologymentioning
confidence: 99%
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“…Since the perichondral ring is thin, the wide surface area of the undulating, interlocking mammillary processes guarantee most of the internal support of the normal physis. On the other hand, SCFE is characterized by physeal widening (as much as 12 mm, with normal range 2–6 mm), a widened hypertrophic zone comprising 60%–80% of physeal height, enlargement of chondrocytes, cellular column disorganization, higher proteo-glycan and extracellular matrix concentrations in the physis, and widespread disruption in chondrocyte differentiation and endochondral ossification 8. Radiographic physeal widening underlines a mechanically weakening of the physis that is susceptible to unlocking mammillary processes, resulting in further destabilization.…”
Section: Etiology and Histopathologymentioning
confidence: 99%
“…Anatomically, it always stands below the foramina for the lateral epiphyseal vessels, and is postulated to confer mechanical strength to the physeal plate. For this reason, it is theorized to be crucial for physeal stability, but it decreases in size and surface area during childhood and adolescence as peripheral physeal cupping increases 8. Liu et al9 postulated that the epiphysis rotates internally on the epiphyseal tubercle and that a widened physis could contribute to epiphyseal dislodgement.…”
Section: Etiology and Histopathologymentioning
confidence: 99%
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“…Slipped upper femoral epiphysis (SUFE) is an important adolescent hip disorder encountered in orthopaedic surgical practice. 1 2 SUFE can be categorised as a Salter-Harris type fracture, 3 characterised by the slippage of the proximal femoral metaphysis anteriorly and superiorly relative to the epiphysis. 4 The epiphysial plate is usually widened due to the presence of an unusually large hypertrophic zone.…”
Section: Introductionmentioning
confidence: 99%
“…[ 6 ] A high index of suspicion is needed to diagnose this condition in adolescents and young adults when they present with hip pain and a limping gait. [ 7 ] Most of these patients require endocrine assessment to rule out hormonal deficiencies. [ 1 ]…”
Section: Discussionmentioning
confidence: 99%