“…The concept of "small-scale/micro-scale" experiments was proposed since the 1940s, (Wright and Eastcott, 1949;Stock, 1953;Horak and Crist, 1975) However, in the 1990s this concept rapidly expanded, and various reactions and chemistry equipment for small-scale/micro-scale experiments were developed (Kelkar and Dhavale, 2000) Additionally, various techniques were collected in the microscale laboratory in the Journal of Chemical Education (Zipp, 1989) and a book was published by the Royal Society of Chemistry (Skinner, 1997). At an early stage, the experiments were intended for middle/high school students (Grønneberg et al, 2006;Supasorn, 2015) A variety of experiments and demonstrations has been developed to promote science awareness (Néel et al, 2015;Chien et al, 2018) and demonstration (Lee and Wiener, 2011). After a while, the experiments were extended to higher levels of education (Flash, 1990) and various chemical processes were changed into small-scale procedures such as distillation (Schwartz, 1992) and the extraction of products (McKenzie et al, 2004).…”