A QS or QR pattern in the absence of myocardial infarction is frequently present in lead V3 and occasionally in lead V4. Exploration by means of multiple chest and abdominal unipolar leads and vectorcardiograms revealed that in almost all such cases, the vector of the initial portions of the QRS complex is directed downwards. Accordingly, in the absence of infarction, patients presenting this pattern almost invariably showed an initial R wave in the leads recorded from positions below the standard level of V3 and V4. The vast majority of patients with myocardial infarction with a similar QRS pattern showed a Q wave in the lower leads. Consideration of vertical components of cardiac voltages may be helpful in the interpretation of the precordial leads.T HE PRESENCE of a QS pattern or of an abnormally deep and wide Q wave (deeper than 25 per cent of succeeding R wave and wider than 0.04 second) in precordial leads V3 to V6 is usually, although not invariably, attributed to myocardial infarction. Occurrence of a QS pattern or of a significant Q wave in leads V3 and V4 and on some occasions even in leads V5 and V6, in the absence of myocardial infarction, has been demonstrated in cases of left ventricular hypertrophy,1' , 12, 14, 15, 28 hypertrophy or dilatation of the right ventricle8 10, 12, 13, 19-22, complete or "incomplete" left bundle branch block,16' 17, 18, 23-26 right bundle branch block,23 and displacement of the heart.15 In his study of electrocardiograms which may be mistaken for myocardial infarction, Myers emphasized the occurrence of these patterns on several occasions.