2015
DOI: 10.1016/j.jff.2015.05.042
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SMEAF attenuates the production of pro-inflammatory mediators through the inactivation of Akt-dependent NF-κB, p38 and ERK1/2 pathways in LPS-stimulated BV-2 microglial cells

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Cited by 39 publications
(32 citation statements)
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“…could enhance the expression of SIRT1, inhibit activity of NF-κB and improve diabetes mellitus (Liu et al, 2014). Chronic hypoglycemia causes alteration on metabolism and hemorheology, which response to the activation of NF-κB and abnormal secretion of proinflammatory cytokines, finally results in inflammation and oxidative stress (Berghe et al, 2006;Supriady et al, 2015). Thus, the up-regulation of SIRT1 Fig.…”
Section: Discussionmentioning
confidence: 99%
“…could enhance the expression of SIRT1, inhibit activity of NF-κB and improve diabetes mellitus (Liu et al, 2014). Chronic hypoglycemia causes alteration on metabolism and hemorheology, which response to the activation of NF-κB and abnormal secretion of proinflammatory cytokines, finally results in inflammation and oxidative stress (Berghe et al, 2006;Supriady et al, 2015). Thus, the up-regulation of SIRT1 Fig.…”
Section: Discussionmentioning
confidence: 99%
“…Gas chromatography–mass spectrometry analysis (GC‐MS) was performed to profile the possible bioactive compounds present in MUM273b extract (Supriady, Kamarudin, Chan, Goh, & Kadir, ). The detection involved the use of the Agilent Technologies 6980N (GC) equipped with 5979 Mass Selective Detector (MS), HP‐5MS (5% phenyl methyl siloxane) capillary column of dimensions 30.0 m × 250 µm × 0.25 µm and helium as carrier gas at 1 ml/min.…”
Section: Methodsmentioning
confidence: 99%
“…Gas chromatography–mass spectrometry (GC–MS) analysis was performed in accordance with our previous developed method with slight modification ( Supriady et al, 2015 ). The machine used was Agilent Technologies 6980N (GC) equipped with 5979 Mass Selective Detector (MS), HP-5MS (5% phenyl methyl siloxane) capillary column of dimensions 30.0 m × 250 μm × 0.25 μm and used helium as carrier gas at 1 mL/min.…”
Section: Methodsmentioning
confidence: 99%