The main objective of this study is to empirically investigate the relationship between female labor force participation (FLFP) and female total fertility rate (FTFR) for the ASEAN-6 countries from the period 1995 to 2013. The Fully Modify OLS (FMOLS) has been applied to explore the cointegration and causality between the suggested variables. The contegration results confirm that the female labor force participation rate and total female fertility rate are cointegrated for the panel of ASEAN-6 countries. Whereas, long-run Granger causality confirm the causality run from the female total fertility rate to the female labor force participation rate. Moreover, the results show that 1percent increase in the female total fertility rate causes in a 0.44 percent decrease in the female labor force participation rate for the ASEAN-6 countries. The FTFR highest negative effect observed in Indonesia and smallest observed in Thailand. The results of FMOLS confirm the long run panel relationship between female labor force and total female fertility rate.