2017
DOI: 10.1016/j.joen.2016.09.023
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Sodium Hypochlorite Accident: A Systematic Review

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Cited by 144 publications
(149 citation statements)
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“…The use of sodium hypochlorite to remove fluorosis stains has been described in the literature . However, care must be exercised when using sodium hypochlorite because it oxidizes the tissues that it comes in contact with resulting in hemolysis, ulceration, inhibition of neutrophil migration, and destruction of endothelial cells and fibroblasts …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The use of sodium hypochlorite to remove fluorosis stains has been described in the literature . However, care must be exercised when using sodium hypochlorite because it oxidizes the tissues that it comes in contact with resulting in hemolysis, ulceration, inhibition of neutrophil migration, and destruction of endothelial cells and fibroblasts …”
Section: Discussionmentioning
confidence: 99%
“…60,[96][97][98] However, care must be exercised when using sodium hypochlorite because it oxidizes the tissues that it comes in contact with resulting in hemolysis, ulceration, inhibition of neutrophil migration, and destruction of endothelial cells and fibroblasts. 99,100 Microabrasion consists of the removal of defects, through an abrasion and a chemical erosion of the superficial layer of the enamel, being considered a safe and minimally invasive technique. 101 The location and depth of the stain or spot are the most important factors for a successful treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Concurrently, the empirical support for the estimation that a systematic higher frequency of adverse effects when using a higher concentration of NaOCl has been questioned (Guivarc'h et al ). A systematic review of available evidence revealed that neither 5.25% NaOCl nor 5.25% NaOCl combined with 3% H2O2 had any significant different impact on postoperative pain from 3 to 14 days after treatment compared to saline solution (Fedorowicz et al ).…”
Section: Introductionmentioning
confidence: 99%
“…If NaOCl comes into contact with tissue, it rapidly oxidizes the surrounding living tissue and triggers rapid hemolysis, inhibits neutrophil migration, and damages endothelial and fibroblast cells. 2 The higher the concentration of NaOCl, the higher the anti-bacterial effect and tissue dissolution, and also the higher the toxicity. 3 Moreover, the very low concentrations of NaOCl (>0.01%) present in in vitro cell culture cause the death of human fibroblast cells.…”
Section: Introductionmentioning
confidence: 99%