Solar Dermatitis

Lamb, John H.

doi:10.1001/archderm.1957.01550140011003

Cited by 31 publications

(7 citation statements)

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“…The male:female sex ratio was 1:4.5. Of the 100 patients, majority of the study subjects (36%) were in the age group of [21][22][23][24][25][26][27][28][29][30] (Figure 1). The age of subjects varied from 10 years to 65 years and mean age of the study population was 32.80+/-12.62 years.…”

Section: Resultsmentioning

confidence: 99%

“…27 Lamb et al have observed plaque to be the most common while Kontus et al found papular type to be very common. 28,29 In a study by Guarrera et al, papules (72.4%) were the commonest lesions followed by vesicles (8.5%). 30 Like all the studies which we have mentioned above, papules were the commonest presentation in our study.…”

Section: Morphology Of the Lesionsmentioning

confidence: 96%

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A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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Introduction: Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. The prevalence of PMLE varies from 5% to 15% in various studies across the world and in India it is 0.56%.Objective: The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption.Material and Method: A cross sectional prospective study was conducted in Dermatology OPD between April 2015 and June 2016. A total of 100 patients with symptoms and signs of PMLE were included in the study. Data were coded and analyzed.Results: Majority of the cases in our study were in the age group of 21 - 30 years (36%). It was more common in females (82%) when compared with males (18%). Occupation of most of the patients (29%) was farmers in our study population. Positive family history of PMLE was seen in 11% of the study population. The commonest form was the papular type (46%) and the second most common type was plaque type (17%). Regarding the distribution of lesions, about 51% of our study subjects had polymorphic lesions confined to only one area of their body mostly forearm (25%) followed by face (12%).Conclusion: The prevalence of PMLE was 1.34% in our study population. Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.

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Section: Resultsmentioning

confidence: 99%

Section: Morphology Of the Lesionsmentioning

confidence: 96%

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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“…Epstein [7,8] was the first whose classical experiments supported the photoallergic concept of the disease suggested in 1926 [4,23], Since that time a lot of studies presented further evi dence [14,15,24,29], Some of them pre sumed the role of a hypersensitive reaction of delayed type in producing the skin lesions [5,6,15,24,29],…”

Section: Discussionmentioning

confidence: 99%

A Study on Cell-Mediated Immunity in Polymorphic Light Eruption

Horkay¹,

Krajczár²,

Bodolay

et al. 1983

Dermatology

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Polymorphic light eruption (PLE) can be defined as a delayed abnormal response to sunlight. In this paper some features of the presumable immune response were studied in 55 patients with PLE and the results were compared with the findings available in 58 cases with porphyria cutanea tarda (PCT). The mean intracutaneous reactivity index measured by skin tests of delayed type was normal in both diseases. The number of the active and total E-rosette-forming peripheral lymphocytes was significantly lower in the active stage of PLE whereas in remission normal values were found. In active PCT only the number of the total E-rosette-forming cells was decreased. The percentage of lymphocytes with so-called dot-like α-naphthyl acetate esterase enzyme reaction was reduced significantly in the active stage of PLE whereas in remission their number was normal. Changes observed in PLE seem to be functional and suggest the involvement of T lymphocytes in some phases of the hypersensitive cutaneous reaction induced by sunlight.

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“…Dermal oedema was noted in 15 cases. Lamb et al 16 described 28 patients with PMLE, microscopic sections from these biopsies showed parakeratosis (4/15 cases), atrophy (12/15 cases), follicular plugging (number of cases not specified), either intercellular or intracellular oedema (10/15 cases), vacuolar alteration (5/15 cases), papillary dermal oedema (14/15 cases), dilated blood vessels and a dense perivascular infiltrate. Wright et al 17 .…”

Section: Methodsmentioning

confidence: 99%

The Study of Clinical Variations and Histopathological Findings in Polymorphous Light Eruption

Lal¹,

Devi²,

Suhasini³

2016

jebmh

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BACKGROUND Epstein. S in 1942 described PMLE under the name of Prurigo aestivalis. He first hypothesised that PMLE represents a form of delayed-type hypersensitivity response to an endogenous, cutaneous UV-induced antigen, because of the hours or days delay between sun exposure and manifestation of symptoms, and the histological appearance of lesional skin. Firm evidence; however, has been lacking and the responsible allergen has not been identified. PMLE a specific entity encompassing six clinical manifestations: Small erythematous papulovesicles, eczematous lesions, large papules, oedematous plaques, prurigo nodules and erythema multiforme-like lesions. The histological features of PMLE are characteristic, but not pathognomonic and vary with the different clinical presentation. A sincere effort has been put in this study to understand the clinical and histopathological features of polymorphic light lesions. The study is intended to help the practising physicians and dermatologists to diagnose the pathology on time and intervene before it develops into complications. METHODS Material for the present study consisted of 100 cases of clinically diagnosed untreated cases of polymorphous light eruption, who were attending the skin and STD and Leprosy Department, Kakatiya Medical College, Warangal, during January 2014 to Dec 2014 were selected for this study. The patients were selected randomly irrespective of age, sex, socioeconomic status. RESULTS Histopathology showed perivascular lymphocytic infiltration in the dermis in majority of our cases (93.33%) and clinicohistopathological correlation was observed in most cases; hence apart from clinical examination, histopathological examination plays an important role in diagnosing PMLE. CONCLUSION 56 percent of the patients complained pruritus followed by burning. The study was similar to other studies in comparison.

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Solar Dermatitis

Cited by 31 publications

References 4 publications

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

A Study on Cell-Mediated Immunity in Polymorphic Light Eruption

The Study of Clinical Variations and Histopathological Findings in Polymorphous Light Eruption

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