Solitary plexiform neurofibroma of the oral cavity

Alatlı, Canan; Öner, B.; Ünür, Meral; Erseven, Gülçin

doi:10.1016/s0901-5027(06)80036-6

Cited by 29 publications

(23 citation statements)

References 5 publications

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“…Few cases are reported on the palate [12,13], despite a more common occurrence in the tongue [2,[12][13][14]. They are slow-growing, nodular, sessile, and mobile tumors, usually painless, although pain or numbness may occur due to nerve compression [13]. Our case too showed similar clinical characteristics of painless, sessile, nodular, smooth pink colored, discrete, firm mass.…”

Section: Discussionsupporting

confidence: 60%

“…It is believed that the frequency of oral solitary neurofibromas not associated with neurofibromatosis-1 is low [2]. Few cases are reported on the palate [12,13], despite a more common occurrence in the tongue [2,[12][13][14]. They are slow-growing, nodular, sessile, and mobile tumors, usually painless, although pain or numbness may occur due to nerve compression [13].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Solitary Neurofibroma of the Soft Palate: A Rare Entity

Ramdurg

Puranik

Dantu

et al. 2016

Indian J Otolaryngol Head Neck Surg

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The solitary neurofibroma is a benign tumor of neuronal origin uncommonly reported in the oral cavity. The possible association of this neoplasia with systemic pathologies, such as von Recklinghausen's disease and multiple endocrine neoplasia, makes its diagnosis fundamental. Solitary isolated neurofibroma of the soft palate not associated with von Recklinghausen's disease is an unusual tumor and probably only four cases have been reported in English literature previously. To the best of our knowledge, our case of soft palate neurofibroma in 17-year-old male represents the fifth reported in English literature, for which complete surgical excision was achieved with uneventful healing.

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Section: Discussionsupporting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Solitary Neurofibroma of the Soft Palate: A Rare Entity

Ramdurg

Puranik

Dantu

et al. 2016

Indian J Otolaryngol Head Neck Surg

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“…Neurofibromas can be multiple or solitary. The tumor's most frequent location is the skin and its multiple appearance is highly associated with von Recklinghausen's disease and poliglandular syndrome MEN III [5-9]. It mainly appears in the third decade of life although occurrence between 10 months and 70 years old has been described.…”

Section: Epidemiologymentioning

confidence: 99%

“…Treatment of choice is surgical excision of the solitary lesions, trying to conserve the nerve from which the tumor originates [5]. Malignant transformation of solitary neurofibroma is extremely rare.…”

Section: Treatment and Prognosismentioning

confidence: 99%

Solitary submucous neurofibroma of the mandible: review of the literature and report of a rare case

et al. 2009

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Solitary neurofibroma is a rare benign non-odontogenic tumor. Particularly in the oral cavity, neurogenic tumors are rare, especially if they are malignant. Neurofibromas may present either as solitary lesions or as part of the generalised syndrome of neurofibromatosis or von Recklinghausen's disease of the skin. Clinically, oral neurofibromas usually appear as pediculated or sessile nodules, with slow growth and mostly without pain. The diagnosis can be confirmed by histological examination. Neurofibromas are immunopositive for the S-100 protein, indicating its neural origin. Treatment is surgical and the prognosis is excellent. For illustration a rare case of a solitary neurofibroma in the mandible is presented.

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“…When solitary plexiform neurofibroma occurs in patients without stigmata or family history of NF-1, the tumor probably represents the segmental form of NF-1 caused by a later somatic mutation (6)(7)(8)(9). A review of the literature showed that, particularly within the oral cavity, solitary plexiform neurofibroma not associated with NF-1 is exceedingly rare (4,7,(10)(11)(12). This article describes an unusual case of isolated plexiform neurofibroma in a female patient with no other manifestation or family history of NF-1 and discusses the importance of differentiating between isolated and NF-1-associated neurofibromas.…”

Section: Introductionmentioning

confidence: 99%