In this paper I criticize one of the most convincing recent attempts to resist the underdetermination thesis, Laudan's argument from indirect confirmation. Laudan highlights and rejects a tacit assumption of the underdetermination theorist, namely that theories can be confirmed only by empirical evidence that follows from them. He shows that once we accept that theories can also be confirmed indirectly, by evidence not entailed by them, the skeptical conclusion does not follow. I agree that Laudan is right to reject this assumption, but I argue that his explanation of how the rejection of this assumption blocks the skeptical conclusion is flawed. I conclude that the argument from indirect confirmation is not effective against the underdetermination thesis.Underdetermination of theory by empirical evidence has long been a challenging problem for epistemology and realism. Recent approaches to underdetermination 1 present the argument as follows:(1) For any theory T, there is another theory T′ such that, given any empirical evidence E, T and T′ are empirically equivalent with respect to E. (2) Empirically equivalent theories warrant belief to the same degree.Therefore, the sceptical conclusion: empirical evidence is unable to guide regarding which theory to believe. Of course, additional criteria (theoretical simplicity, explanatory power, etc.) can be invoked to break the tie. However, the anti-realist claims that this is not a very convincing reply, as these criteria are pragmatic, not epistemic: one still needs to prove that there is a link between pragmatic concerns and what is true. Premise (1) has been traditionally considered problematic for the supporter of the underdetermination thesis. This premise