Some complexes of Zink (II) and Manganese (II) with schiff base derived from nicotinamide, synthesis and characterization, antibacterial evaluation

Abed, Rana R.; Ahmed, Amena E.

doi:10.5958/0974-360x.2021.00304.8

Cited by 3 publications

(2 citation statements)

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“…[11][12][13][14][15] Moreover, many studies showed that the existence of more than two heterocyclic units may lead to an increase the antimicrobial activity significantly. 16 Schiff bases are compounds carrying azomethine functional group 17 (C=N), Schiff bases obtained from complexes derived heterocycles have a great importance in the field of pharmaceutical industries due to versatile uses in synthetic intermediates and the wide range of biological properties. 18 For example, antifungal, 19 antibacterial, 20 analgesic and anti-inflammatory, 21 anticonvulsant, 22 anticancer 23 and antituberculosis activities.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Few New Substituted 1,3,4-Oxadiazoles 1,2,4-Triazoles and Schiff Bases via Chalcone Compounds

Ahmed¹,

Mahmood²,

Aziz³

2022

IJDDT

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Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Few New Substituted 1,3,4-Oxadiazoles 1,2,4-Triazoles and Schiff Bases via Chalcone Compounds

Ahmed¹,

Mahmood²,

Aziz³

2022

IJDDT

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“…Schiff bases are compounds prepared by the reaction of aldehydes or ketones with amines, in which the carbonyl group is replaced by an azomethine group, and the nitrogen atom is attached to an aryl or alkyl (1). Oxazepine is a heterocyclic seven-membered compound containing two atoms (O, N): the oxygen atom is in position 1 and the nitrogen in position 3 (2).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, identification, and cytotoxicity effect of Oxazapine scaffolding

Azzawi

Hussein

2022

ijhs

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The research includes the preparation of two Schiff bases MA (2-1) and some of their derivatives from the reaction of para-bromobenzaldehyde or para-methoxy benzaldehyde with stoichiometric 5-methyl pyrazole-3-amino in the presence of glacial acetic acid. Then the corresponding oxazepine rings MA (6-3) were prepared from each MA (2-1) with maleic anhydride or phthalic anhydride. The prepared chemical formulas were spectroscopically confirmed using FTIR and 1HNMR spectroscopy. The biological activity of MA5 had tested against MDA breast cancer and REF healthy cells at seven concentrations (500,250,125,62.5,31.5,15.5,7.5) µg / ml. The compound showed a high inhibition against cancer cells, so this makes it a candidate as a drug for future cytotoxicity.

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Characterization and Antibacterial Evaluation of New Complexes of Nicotinamide semicarbazon Manganese (II), Zinc (II), Silver (I) Synthesizes

Ali¹,

Mohammed²,

Jasim³

et al. 2023

RJPT

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The purpose of this research article is to explore the coordination chemistry and antibacterial activity of six new mononuclear complexes formed via reacting Ag(I), Zn(II), and Mn(II) ions with the Schiff base as a ligand (Nicotinamide- semicarbazone) in a (1:2) ratio in both acidic and basic medium., the six complexes are characterized by elemental analysis(CHN), atomic absorption spectroscopy, Infrared spectroscopy, (1H NMR). and different Technique such as melting point, conductivity measurements, Molar refraction The suggested formula of the complexes were [M(NASC)2] Xn in natural medium and [M(NASC)2] in basic medium, M = Ag n=1, M= Zn, Mn n=2, X=NO3 NASC = Nicotinamide- semicarbazone. It was a tridentate ligand it coordinated onto metal ions via three nitrogen atoms, producing off white or yellow complexes with only an octahedral geometry. These complexes and their ligands were evaluated as antibiotics against a series of medically significant bacteria, and both were found to be very effective.

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Some complexes of Zink (II) and Manganese (II) with schiff base derived from nicotinamide, synthesis and characterization, antibacterial evaluation

Cited by 3 publications

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Synthesis and Characterization of Few New Substituted 1,3,4-Oxadiazoles 1,2,4-Triazoles and Schiff Bases via Chalcone Compounds

Synthesis and Characterization of Few New Substituted 1,3,4-Oxadiazoles 1,2,4-Triazoles and Schiff Bases via Chalcone Compounds

Synthesis, identification, and cytotoxicity effect of Oxazapine scaffolding

Characterization and Antibacterial Evaluation of New Complexes of Nicotinamide semicarbazon Manganese (II), Zinc (II), Silver (I) Synthesizes

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