Sonographic discrimination of dementia with Lewy bodies and Parkinson's disease with dementia

Walter, Uwe; Dressler, Dirk; Wolters, Alexander; Wittstock, Matthias; Greim, B.; Benecke, Reiner

doi:10.1007/s00415-005-0023-9

Cited by 85 publications

(57 citation statements)

References 41 publications

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“…In patients with DLBD and PDD the width of the third ventricle and frontal horn was signifi cantly larger than for PD patients without dementia. This enlargement correlated with UPDRS scale in PDD 47 .…”

Section: Dementia With Lewy Bodiessupporting

confidence: 57%

Transcranial Sonography in Movement Disorders

Bártová¹,

Školoudík²,

Bar³

et al. 2008

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Section: Dementia With Lewy Bodiessupporting

confidence: 57%

Transcranial Sonography in Movement Disorders

Bártová¹,

Školoudík²,

Bar³

et al. 2008

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…Patients with LBD [60] and CBD [26] have been reported to share the same echo feature with IPD patients. However, the hyperechogenicity of the LN is commonly seen in patients with CBD whereas patients with IPD only rarely have this feature.…”

Section: Resultsmentioning

confidence: 99%

“…Unfortunately, their sensitivity and specificity are not sufficiently high [8,24]. Moreover, neuroimaging methods, such as CT, MRI and PET, do not discriminate between IPD and DLB [60].…”

Section: Tcs In Apsmentioning

confidence: 99%

See 1 more Smart Citation

Update on Transcranial Sonography Applications in Movement Disorders

Godani¹,

Canavese²,

Sette³

et al. 2014

J Diagn Imaging Ther

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Over the past 20 years transcranial B-mode sonography (TCS) of brain parenchyma is being increasingly used as a diagnostic tool in movement disorders. The most widely recognised finding for movement disorders has been an increase in echogenicity of the substantia nigra, an area of the midbrain that is affected in idiopathic Parkinson's disease (IPD). This finding has enabled a reliable diagnosis of IPD with high predictive values. Other sonographic features -such as hypoechogenicity of the brainstem raphe and hyperechogenicity of the lentiform nucleus -might help to increase the differential diagnosis of IPD and other movement disorders. In comparison with other neuroimaging modalities such as magnetic resonance imaging (MRI) and computed tomography (CT), TCS can currently be performed with portable machines and has the advantages of non-invasiveness with high resistance to movement artifacts. In distinct brain disorders TCS detects abnormalities that cannot be visualized -or can only be visualized with significant effort -with other imaging methods. This present update summarizes the current methodological standards and defines the assessment of diagnostically relevant deep brain structures such as substantia nigra, brainstem raphe, basal ganglia and ventricles

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“…In addition to PD, corticobasal ganglionic degeneration (CBD), DLB and many other neurodegenerative diseases also have SN+. Walter et al [19] believed that the features of SN+ of DLB are the areas of SN+ ≥ 0.25cm 2 , and the bilateral asymmetry index <1.15. It is suggested that the SN+ is related to iron metabolism rather than Lewy body accumulation.…”

Section: Discussionmentioning

confidence: 99%