Soroprevalência do vírus linfotrópico-T humano tipo I entre gestantes em Goiânia, GO, Brasil

Oliveira, Sebastião Rodrigues de; Avelino, Mariza Martins

doi:10.1590/s0100-72032006000800005

Cited by 11 publications

(7 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…HTLV-1 infection was higher among primigravidae (3/5-60.0%), in contrast to data reported by Oliveira and Avelino [35], Figueiró-Filho et al [36], and Sequeira et al [47], who observed a higher number of infected pregnant women with multiple pregnancies in Goiás, Mato Grosso, and Pará, respectively.…”

Section: Discussioncontrasting

confidence: 73%

“…In recent years, molecular methods for the diagnosis of different types of infectious agents have revolutionized diagnostic medicine because of their high sensitivity, specificity, and rapidity [33]. This study is the first to use PCR as a molecular diagnostic screening method for HTLV-1 in pregnant Brazilian women, while previous studies have used this technique only as a confirmatory and discriminatory test [26,30,[34][35][36][37][38][39]. In the present study, the PCR technique detected a prevalence of 0.7% (5/713) of HTLV-1 in the pregnant women who were analyzed.…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

Molecular detection of human T cell lymphotropic virus type 1 in pregnant women from Maranhão state, Brazil

et al. 2020

View full text Add to dashboard Cite

The human T cell lymphotropic virus (HTLV) has a worldwide distribution. HTLV is endemic in some states in the northeastern region of Brazil. This study investigated the prevalence of HTLV-1/2 in 713 pregnant women attended at the Central Laboratory of Public Health of Maranhão (LACEN-MA) between February 2015 and May 2017. Serological screening was performed by chemiluminescent microparticle immunoassay (CMIA), and reactive sera were subsequently confirmed by Western blot (WB) analysis. Five samples were determined to be HTLV-1/2-reactive by CMIA analysis, while in the WB analysis, three sera were positive for HTLV-1, and two were indeterminate. The polymerase chain reaction (PCR) analysis used to detect HTLV-1 proviral DNA showed a specific 336 base pair fragment for HTLV-1 in all CMIA-reactive serum samples. PCR products were purified and sequenced. We observed a 0.7% molecular prevalence of HTLV-1 infection. The average age of the HTLV-1-positive pregnant women was 25.6 ± 8.2 years, and the average age of the HTLV-1-negative pregnant women was 24.3 ± 6.2 (p = 0.60). We observed that there was no association of HTLV-1 infection with age, ethnicity, marital status, educational level, family income, age of first sexual intercourse, previous pregnancy, breastfeeding, intravenous drug use by partner, history of blood transfusions, or use of condoms. The prevalence of HTLV-1 observed in pregnant women demonstrated the need to implement public health policies for the screening of HTLV-1/2 in prenatal care and counseling to avoid breastfeeding by infected women; this approach could control vertical transmission and reduce the spread of this virus in the population.

show abstract

Section: Discussioncontrasting

confidence: 73%

Section: Discussionmentioning

confidence: 94%

Molecular detection of human T cell lymphotropic virus type 1 in pregnant women from Maranhão state, Brazil

et al. 2020

View full text Add to dashboard Cite

show abstract

“… 28 At national level, HTLV seroprevalence in pregnant/parturient women is heterogeneous and depends on the region. It ranges from 0.1% in Mato Grosso do Sul, 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 Mato Grosso, 7 Goiânia 30 and Botucatu (SP) 7 to 1.7% in Vitória (ES). 21 HTLV screening in health institutions is performed only in the prenatal follow-up, but pregnant women show low level of information ablout previous tests.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence and factors associated with Human Immunodeficiency virus, Human T lymphotropic virus and Hepatitis B/C infections in parturient women of Salvador – Bahia, Brazil

Vargas

Bastos

Guimarães

et al. 2020

The Brazilian Journal of Infectious Diseases

View full text Add to dashboard Cite

“…In Brazil, HTLV-1/2 prevalence in pregnant women can reach 1% in certain regions of the country (Table 1) 159,[179][180][181][182][183][184][185][186][187][188][189][190][191][192][193][194][195][196] . Despite reports about the development of HTLV-associated diseases in pregnancy (HAM, ATL), there is no consistent evidence about the impact on the pregnancy-puerperium cycle 23 .…”

Section: Pregnant Womenmentioning

confidence: 99%

Brazilian Protocol for Sexually Transmitted Infections 2020: human T-cell lymphotropic virus (HTLV) infection

Rosadas

Brites

Arakaki-Sanchéz

et al. 2021

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

This article addresses the Human T-lymphotropic virus (HTLV). This subject comprises the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health. HTLV-1/2 infection is a public health problem globally, and Brazil has the largest number of individuals living with the virus. HTLV-1 causes several clinical manifestations of neoplasm (adult T-cell leukemia/lymphoma) and inflammatory nature, such as HTLV-1-associated myelopathy and other manifestations such as uveitis, arthritis, and infective dermatitis. These pathologies have high morbidity and mortality and negatively impact the quality of life of infected individuals. This review includes relevant information for health authorities professionals regarding viral transmission, diagnosis, treatment, and monitoring of individuals living with HTLV-1 and 2 in Brazil.

show abstract

Soroprevalência do vírus linfotrópico-T humano tipo I entre gestantes em Goiânia, GO, Brasil

Cited by 11 publications

References 20 publications

Molecular detection of human T cell lymphotropic virus type 1 in pregnant women from Maranhão state, Brazil

Molecular detection of human T cell lymphotropic virus type 1 in pregnant women from Maranhão state, Brazil

Seroprevalence and factors associated with Human Immunodeficiency virus, Human T lymphotropic virus and Hepatitis B/C infections in parturient women of Salvador – Bahia, Brazil

Brazilian Protocol for Sexually Transmitted Infections 2020: human T-cell lymphotropic virus (HTLV) infection

Contact Info

Product

Resources

About