Many irrigated agricultural areas seek strategies to prolong the lifespan of their groundwater resources. However, it is unclear how lagged responses, such as reduced groundwater recharge caused by more efficient irrigation, may impact the ultimate effectiveness of these initiatives. Here, we use a variably saturated groundwater model to: 1) analyze aquifer responses to pumping reductions, 2) quantify time lags between reductions and water level responses, and 3) identify the physical controls on lagged responses. We explore a range of plausible model parameters for an area of the High Plains Aquifer (USA) where stakeholderdriven conservation has slowed groundwater depletion. We identify two types of lagged responses that reduce the long-term effectiveness of groundwater conservation. When vertical hydraulic conductivity (Kz) is > 3.5 x 10 -3 m d -1 , more efficient irrigation reduces groundwater recharge on sub-decadal timescales (recharge-dominated response). By contrast, when Kz is < 3.5 x 10 -3 m d -1 , changes in recharge are negligible, but pumping reductions alter the lateral flow between the groundwater conservation area and the surrounding regions over decadal timescales (lateral-flow-dominated response). For the modeled area, we found that a pumping reduction of 30% resulted in median usable lifetime extensions of 20 or 25 years, depending on the dominant lagged response mechanism (recharge-vs. lateral-flow-dominated). These estimates are far shorter than estimates made without accounting for the lagged responses. Our results indicate that conservation-based pumping reductions can extend aquifer lifespans, but lagged responses can create a sizable difference between the initial and long-term effectiveness of those conservation measures.