Spatial Epidemiology of the Syphilis Epidemic in Toronto, Canada

Gesink, Dionne; Wang, Susan; Norwood, Todd A.; Sullivan, Anna; Al-Bargash, Dana; Shahin, Rita

doi:10.1097/olq.0000000000000196

Cited by 30 publications

(21 citation statements)

References 27 publications

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“…It also joins recent work in translational science, which seeks to improve our understanding of STI transmission dynamics and translate these findings into specific recommendations for the targeted control of STIs (33, 42). Future research should focus on providing a better understanding of the stability of the identified venues and identifying other important features of venues which distinguish places with ongoing transmission.…”

Section: Discussionmentioning

confidence: 92%

Social place as a location of potential core transmitters—implications for the targeted control of sexually transmitted disease transmission in urban areas

Jennings

Polk

Fichtenberg

et al. 2015

Annals of Epidemiology

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Purpose Places are an important determinant of risk for sexually transmitted infection (STI) acquisition and transmission. We sought to identify social places that are critical for targeted STI control activities. The objective of this study was to determine whether sex partner meeting places characterized by drug markets, sex markets and separately, drug and/or sex markets were more likely to have potential core transmitters as compared to other sex partner meeting places in one urban setting. Methods In 2008–2009, heterosexual sex partner places or venues were identified in Baltimore, MD using a venue-based study approach. Results 1,334 participants aged 18–35 years were enrolled at 85 venues. 39 potential core transmitters were identified and 31% of venues had at least one potential core transmitter. In final age- and gender-adjusted models, core transmitters were significantly more likely to be identified at drug markets (OR 1.37; 95% CI 1.23, 1.53), sex markets (OR 1.27; 95% CI 1.14. 1.41) and drug and/or sex markets (OR 1.49; 95% CI 1.32, 1.68). Conclusions This study identified key characteristics of venues, such as drug and sex market activity, that may be important in identifying places for the targeted control of STI transmission.

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Section: Discussionmentioning

confidence: 92%

Social place as a location of potential core transmitters—implications for the targeted control of sexually transmitted disease transmission in urban areas

Jennings

Polk

Fichtenberg

et al. 2015

Annals of Epidemiology

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“…Existe uma íntima relação entre a infecção por sífilis com comportamentos de maior vulnerabilidade, caracterizados principalmente pela exposição a múltiplas parcerias sexuais, ausência de preservativo nas relações, presença de outras ISTs (24) .…”

Section: Descriptoresunclassified

Prevalência De Sífilis Em Mulheres

Silva

Alves²,

Barros³

et al. 2017

revenf

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Objetivo: verificar a prevalência de sífilis em mulheres que realizaram o teste rápido em um serviço de referência de Porto Alegre/RS. Metodologia: estudo quantitativo, descritivo, transversal, realizado com 1300 prontuários de mulheres que realizaram o teste rápido no período de julho de 2012 a abril de 2014. Os dados foram analisados a partir de estatística descritiva.As variáveis categóricas foram expressas em número absoluto e percentual e aquelas com distribuição normal expressas como média ± desvio padrão. Resultados: 103 (7,9%) THE PREVALENCE OF SYPHILIS IN WOMENObjective: To verify the prevalence of syphilis in women who performed the rapid check up at a referral service in Porto Alegre.Methodology: A quantitative, descriptive, cross-sectional study of 103 records of women who performed the rapid check up from July 2012 to April 2014. Data were analyzed using descriptive statistics, categorical variables were expressed in absolute number and Percentage and those with normal distribution expressed as average ± standard deviation. Results: 103 (35.6%) had syphilis. The age ranged from 16 to 76 years, the average was 38.9 ± 12,8 years, 46 (45.1%) had completed secondary education, 31 (30,4%) had a fixed partnership, 35 (34.3 %) already had some type of STD. Conclusions: It is understood that for the control of the disease, the early diagnosis is fundamental and the assistance should be performed immediately in the primary care, aiming at a greater integration and bond with the unit /community/health/team. Descriptors:Sexually Transmitted Diseases, Syphilis, Women's Health. PREDOMINIO DE SÍFILIS EN MUJERESObjetivo: Determinar el predominio de sífilis en mujeres que se sometieron a la prueba rápida en un servicio de referencia en Porto Alegre. Metodología: cuantitativa, estudio descriptivo transversal realizado con 103 registros de mujeres que se sometieron a la prueba rápida de julio de 2012 hasta abril de 2014. Los datos fueron analizados utilizando estadística descriptiva, las variables categóricas se expresan en números absolutos y porcentaje y los que tienen distribución normal expresaron como media ± desviación estándar. Resultados: 103 (35,6%) presentaron sífilis. La edad varió de 16 a 76 años, el promedio fue de 38,9± 12,8 años, 46 (45,1%) habían completado la escuela secundaria, 31 (30,4%) tenían pareja estable, 35 (34,3 %) ya tenía algún tipo de enfermedad de transmisión sexual. Conclusiones: Se entiende que para controlar la enfermedad, el diagnóstico precoz es importante y el servicio debe realizarse inmediatamente en la atención primaria, con el objetivo de una mayor integración y vínculo con el servicio de salud/comunidad/equipo de salud.Descriptores: Enfermedades de Transmisión Sexual, Sífilis, Salud de la Mujer.

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“…Investigation of syphilis incidence requires consideration of re-infection to fully characterize the patterns of population-level transmission and to design interventions. New syphilis cases among HIV co-infected men commonly have a past history of previous syphilis infection [ 8 , 14 , 15 ]. Epidemiological characterization of the rate of first versus subsequent syphilis infections could help to determine to what extent syphilis epidemics are concentrated in core groups experiencing repeated infections.…”

Section: Introductionmentioning

confidence: 99%

High incidence of diagnosis with syphilis co-infection among men who have sex with men in an HIV cohort in Ontario, Canada

et al. 2015

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BackgroundThe re-emergence of syphilis among HIV-positive gay and other men who have sex with men (MSM) requires vigilance. We estimated incidence of and risk factors for first and subsequent syphilis diagnoses among MSM in HIV care in Ontario, Canada.MethodsWe analyzed data from 2,280 MSM under follow-up from 2006 to 2010 in the Ontario HIV Treatment Network Cohort Study (OCS), a multi-site clinical cohort. We obtained syphilis serology results via record linkage with the provincial public health laboratory. Rates were calculated using Poisson regression.ResultsFirst syphilis diagnoses occurred at a rate of 2.0 per 100 person-years (95 % CI 1.7, 2.4; 121 cases) whereas the re-diagnosis rate was 7.5 per 100 person-years (95 % CI 6.3, 8.8; 136 cases). We observed higher rates over time and among men who were aged <30 years, receiving care in the two largest urban centers, or had a previous syphilis diagnosis. Syphilis diagnosis was less common among Indigenous men, men with higher CD4 cell counts, and, for first diagnoses only, among men with less than high school education.ConclusionsCompared to reported cases in the general male population, incidence of a new syphilis diagnosis was over 300 times greater among HIV-positive MSM but year-to-year changes reflected provincial trends. Re-diagnosis was common, suggesting treatment failure or re-infection. Novel syphilis control efforts are needed among HIV-positive MSM.

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Spatial Epidemiology of the Syphilis Epidemic in Toronto, Canada

Abstract: Toronto's syphilis epidemic is mature. Response, resources, and intervention activities should target core and noncore areas.

Cited by 30 publications

References 27 publications

Social place as a location of potential core transmitters—implications for the targeted control of sexually transmitted disease transmission in urban areas

Social place as a location of potential core transmitters—implications for the targeted control of sexually transmitted disease transmission in urban areas

Prevalência De Sífilis Em Mulheres

High incidence of diagnosis with syphilis co-infection among men who have sex with men in an HIV cohort in Ontario, Canada

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