Spatio-temporal pattern of vestibular information processing after brief caloric stimulation

Marcelli, Vincenzo; Esposito, Fabrizio; Aragri, Adriana; Furia, Teresa; Riccardi, Pasquale; Tosetti, Michela; Biagi, Laura; Marciano, Elio; Salle, Francesco Di

doi:10.1016/j.ejrad.2008.01.042

Cited by 50 publications

(43 citation statements)

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“…Simultaneous stimulation shows PBR galvanic current, applied through a pair of electrodes that is attached to the skin, one electrode over each mastoid process (Wardman et al 2003;Moore et al 2006;MacDougall et al 2006;Aw et al 2006). It is also possible to stimulate the vestibular system with caloric stimulation in a neuroimaging study (Fasold et al 2002;Dieterich et al 2003a;Marcelli et al 2009). However, the main advantage of using galvanic vestibular stimulation (GVS), compared to the caloric stimulus, is that GVS acts on vestibular system by firing the primary vestibular neurons, causing a quickly stimulus response.…”

Section: Introductionmentioning

confidence: 99%

Interaction of brain areas of visual and vestibular simultaneous activity with fMRI

et al. 2014

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Static body equilibrium is an essential requisite for human daily life. It is known that visual and vestibular systems must work together to support equilibrium. However, the relationship between these two systems is not fully understood. In this work, we present the results of a study which identify the interaction of brain areas that are involved with concurrent visual and vestibular inputs. The visual and the vestibular systems were individually and simultaneously stimulated, using flickering checkerboard (without movement stimulus) and galvanic current, during experiments of functional magnetic resonance imaging. Twenty-four right-handed and non-symptomatic subjects participated in this study. Single visual stimulation shows positive blood-oxygen-level-dependent (BOLD) responses (PBR) in the primary and associative visual cortices. Single vestibular stimulation shows PBR in the parieto-insular vestibular cortex, inferior parietal lobe, superior temporal gyrus, precentral gyrus and lobules V and VI of the cerebellar hemisphere. Simultaneous stimulation shows PBR in the middle and inferior frontal gyri and in the precentral gyrus. Vestibular- and somatosensory-related areas show negative BOLD responses (NBR) during simultaneous stimulation. NBR areas were also observed in the calcarine gyrus, lingual gyrus, cuneus and precuneus during simultaneous and single visual stimulations. For static visual and galvanic vestibular simultaneous stimulation, the reciprocal inhibitory visual-vestibular interaction pattern is observed in our results. The experimental results revealed interactions in frontal areas during concurrent visual-vestibular stimuli, which are affected by intermodal association areas in occipital, parietal, and temporal lobes.

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Section: Introductionmentioning

confidence: 99%

Interaction of brain areas of visual and vestibular simultaneous activity with fMRI

et al. 2014

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“…Functional neuroimaging studies performed in healthy subjects during caloric and galvanic vestibular stimulation have unanimously demonstrated activation of the posterior insula and temporo-parietal junction (TPJ), that could represent the human homologue of the monkey PIVC (Bense et al, 2001;Bottini et al, 1994Bottini et al, , 1995Bottini et al, , 2001Bucher et al, 1998;Dieterich et al, 2003;Eickhoff et al, 2006b;Emri et al, 2003;Fasold et al, 2002;Fink et al, 2003;Friberg et al, 1985;Hegemann et al, 2003;Indovina et al, 2005;Lobel et al, 1998;Marcelli et al, 2009;Miyamoto et al, 2007;Naito et al, 2003;Petit and Beauchamp, 2003;Schlindwein et al, 2008;Stephan et al, 2005;Suzuki et al, 2001;Tuohimaa et al, 1983;Vitte et al, 1996). These activations centered on the superior temporal gyrus, the posterior and anterior insula, or the inferior parietal lobule (Fig.…”

Section: Vestibular Projections To the "Parieto-insular Vestibular Comentioning

confidence: 99%

“…No neuroimaging study using such methods has so far specifically focused on thalamic activations during vestibular stimulation. However, several neuroimaging studies describing the location of the vestibular cortex in healthy participants have also revealed thalamic activations during caloric (Bottini et al, 2001;Deutschländer et al, 2002;Dieterich et al, 2003;Marcelli et al, 2009;Suzuki et al, 2001) and galvanic (Bense et al, 2001;Bucher et al, 1998;Stephan et al, 2005) stimulation of the peripheral vestibular receptors. In a study using galvanic vestibular stimulation, Bense et al (2001) reported an activation of the paramedian and dorsolateral thalamus, whereas in a study using caloric vestibular stimulation, Dieterich et al (2003) reported an activation of the posterolateral and posteromedial thalamus.…”

Section: Neuroimaging Datamentioning

confidence: 99%

“…We note that it is difficult to conclude about the presence of a primary vestibular cortex, or a core vestibular region in humans, based on existing PET and fMRI studies. Indeed, the poor temporal resolution of PET and fMRI makes it difficult to determine the time course of subcortical and cortical vestibular processing (but see (Marcelli et al, 2009)). Thus, none of these techniques has so far described a sequence of activation across cortical areas, or a simultaneous activation of cortical areas, following a vestibular stimulation.…”

Section: Connections Between Vestibular Cortical Areasmentioning

confidence: 99%

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The thalamocortical vestibular system in animals and humans

Lopez

Blanke

2011

Brain Research Reviews

468

379

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The vestibular system provides the brain with sensory signals about three-dimensional head rotations and translations. These signals are important for postural and oculomotor control, as well as for spatial and bodily perception and cognition, and they are subtended by pathways running from the vestibular nuclei to the thalamus, cerebellum and the "vestibular cortex."The present review summarizes current knowledge on the anatomy of the thalamocortical vestibular system and discusses data from electrophysiology and neuroanatomy in animals by comparing them with data from neuroimagery and neurology in humans. Multiple thalamic nuclei are involved in vestibular processing, including the ventroposterior complex, the ventroanterior-ventrolateral complex, the intralaminar nuclei and the posterior nuclear group 2 0 1 1 ) 1 1 9 -1 4 6 Abbreviations: 3aHv, 3a-hand-vestibular area; 3aNv, 3a-neck-vestibular area; ASS, anterior suprasylvian cortex; DVN, descending vestibular nucleus; FEF, frontal eye fields; Ig, insula granularis; IL, intralaminar nuclei; LD, lateral dorsal nucleus; LGN, lateral geniculate nucleus; LP, lateral posterior nucleus; LVN, lateral vestibular nucleus; MGmc, medial geniculate nucleus, pars magnocellularis; MGN, medial geniculate nucleus; MIP, medial intraparietal area; MST, medial superior temporal area; MT, middle temporal area; MVN, medial vestibular nucleus; PIVC, parieto-insular vestibular cortex; PO, posterior group of the thalamus; Reipt, area retroinsularis pars parietalis; Ri, area retroinsularis; SGN, suprageniculate nucleus; SVN, superior vestibular nucleus; TPJ, temporo-parietal junction; VA, ventroanterior thalamic nucleus; Vim, nucleus ventralis intermedius; VIP R A I N R E S E A R C H R E V I E W S 6 7 (

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“…These clinical data were extended by neuroimaging studies in which healthy humans were exposed to various techniques of vestibular stimulation. Functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) studies revealed activations in the insula, superior temporal gyrus, inferior parietal lobule, somatosensory cortex, cingulate gyrus, frontal cortex, and hippocampus (Bottini et al, 1994;Vitte et al, 1996;Bucher et al, 1998;Lobel et al, 1998;Bense et al, 2001;Suzuki et al, 2001;Deutschla¨nder et al, 2002;Fasold et al, 2002;Dieterich et al, 2003;Emri et al, 2003;Hegemann et al, 2003;Stephan et al, 2005;Eickhoff et al, 2006b;Marcelli et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

The human vestibular cortex revealed by coordinate-based activation likelihood estimation meta-analysis

2012

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Abstract-The vestibular system contributes to the control of posture and eye movements and is also involved in various cognitive functions including spatial navigation and memory. These functions are subtended by projections to a vestibular cortex, whose exact location in the human brain is still a matter of debate . The vestibular cortex can be defined as the network of all cortical areas receiving inputs from the vestibular system, including areas where vestibular signals influence the processing of other sensory (e.g. somatosensory and visual) and motor signals. Previous neuroimaging studies used caloric vestibular stimulation (CVS), galvanic vestibular stimulation (GVS), and auditory stimulation (clicks and short-tone bursts) to activate the vestibular receptors and localize the vestibular cortex. However, these three methods differ regarding the receptors stimulated (otoliths, semicircular canals) and the concurrent activation of the tactile, thermal, nociceptive and auditory systems. To evaluate the convergence between these methods and provide a statistical analysis of the localization of the human vestibular cortex, we performed an activation likelihood estimation (ALE) metaanalysis of neuroimaging studies using CVS, GVS, and auditory stimuli. We analyzed a total of 352 activation foci reported in 16 studies carried out in a total of 192 healthy participants. The results reveal that the main regions activated by CVS, GVS, or auditory stimuli were located in the Sylvian fissure, insula, retroinsular cortex, fronto-parietal operculum, superior temporal gyrus, and cingulate cortex. Conjunction analysis indicated that regions showing convergence between two stimulation methods were located in the median (short gyrus III) and posterior (long gyrus IV) insula, parietal operculum and retroinsular cortex (Ri). The only area of convergence between all three methods of stimulation was located in Ri. The data indicate that Ri, parietal operculum and posterior insula are vestibular regions where afferents converge from otoliths and semicircular canals, and may thus be involved in the processing of signals informing about body rotations, translations and tilts. Results from the meta-analysis are in agreement with electrophysiological recordings in monkeys showing main vestibular projections in the transitional zone between Ri, the insular granular field (Ig), and SII. Ó

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Spatio-temporal pattern of vestibular information processing after brief caloric stimulation

Cited by 50 publications

References 21 publications

Interaction of brain areas of visual and vestibular simultaneous activity with fMRI

Interaction of brain areas of visual and vestibular simultaneous activity with fMRI

The thalamocortical vestibular system in animals and humans

The human vestibular cortex revealed by coordinate-based activation likelihood estimation meta-analysis

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