Special Section Guest Editorial: Advances in Terahertz Biomedical Science and Applications

Sensitivity of Neuroblastoma and Induced Neural Progenitor Cells to High-Intensity THz Radiation

“…The terahertz (THz) spectral region of electromagnetic radiation is commonly referred to as the frequency range between 0.1 and 10 THz, wavelengths between 30 μm and 3 mm, and photon energies from 0.41 to 41 meV. The recent advances in THz generation and detection techniques have led to widespread applications covering medical imaging, diagnostics, and therapy (see reviews [ 1 , 2 , 3 , 4 ]). These applications include the diagnosis of malignant and benign neoplasms [ 5 ], intraoperative neurodiagnostics [ 6 ], determination of the hydration level [ 7 ] and viability of tissue, as well as regulation of the expression of genes associated with systemic inflammatory diseases/cancer [ 8 ], and the application of Escherichia coli bacteria as biosensors for THz radiation [ 9 ].…”

Prism Couplers with Convex Output Surfaces for Nonlinear Cherenkov Terahertz Generation

“…The electromagnetic radiation of the terahertz (THz) frequency range 0.3-10 THz attracts a lot of attention now due to its specific properties and promising applications in various scientific and technological fields. THz waves are non-ionizing, which is very important in biophotonics, medical and security systems [1,2], they pass without absorption through many dielectric packaging materials but demonstrate characteristic absorption lines in other important substances, which is very useful for non-invasive inspection and nondestructive testing systems [3], and they are quite promising for future wireless communication links due to a high bandwidth potential [4]. Among the various methods currently being developed to generate THz radiation, the approaches using pulsed optical lasers [5] allow the most powerful (when pumping the nonlinear crystals [6] or photoconductive antennas [7]) and broadband (under laser-driven generation in the gas plasma [8]) THz radiation within table-top systems to be obtained.…”

Fivefold Peak Power Boost in HBT-Driven GaAs Collapsing-Field-Domain-Based Sub-THz Source

“…Within the last few decades, time-domain spectroscopy (TDS) and time-domain imaging (TDI) have become accessible techniques via the implementation of femtosecond laser-driven pulsed sources [1]- [3]. Their recent applications include biophotonics [4], [5], security scanning [6], and other [7]. While the temporal resolution of such systems reaches hundreds of femtoseconds [8], [9], most TDI/TDS THz setups remain bulky, expensive, and energy-consuming, limiting their real-world applications.…”