Spectrophotometric Determination of Co(II) in Vitamin B12 Using2-(biphenyl-4-yl)-3-((2-(2,4-dinitrophenyl) hydrazono)methyl) imidazo [1,2-a]pyridine as Ligand by Flow Injection–Merging Zone Analysis

Yaseen, Suhair Mohammed; Qassim, Bushra B.; Al-Lami, Naeemah

doi:10.22401/anjs.23.3.04

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…The analytical characteristics of each approach, including the detection limit, correlation coefficient (r), relative standard deviation, and linear range, were determined at the optimal condition 27,28 as shown in Table 7. Numerous PHE standard solutions were used to construct calibration curves, and the technique's main analytical figure of deserts was used.…”

Section: Methods Validationmentioning

confidence: 99%

A New Approach for Developing Spectrophotometric Determination of Phenylephrine Drug in Pure, Pharmaceutics and Serum Samples Using Sodium Periodate as Oxidizing Agent via a Green Method of CFIA/Merging Zone Technique

Hamed,

Qassim

2023

Baghdad Sci.J

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The research involved a rapid, automated and highly accurate developed CFIA/MZ technique for estimation of phenylephrine hydrochloride (PHE) in pure, dosage forms and biological sample. This method is based on oxidative coupling reaction of 2,4-dinitrophenylhydrazine (DNPH) with PHE in existence of sodium periodate as oxidizing agent in alkaline medium to form a red colored product at ʎmax )520 nm (. A flow rate of 4.3 mL.min-1 using distilled water as a carrier, the method of FIA proved to be as a sensitive and economic analytical tool for estimation of PHE. Within the concentration range of 5-300 μg.mL-1, a calibration curve was rectilinear, where the detection limit was 3.252 μg.mL-1, and the RSD% was 4.09. Recovery was 100.55% with a sample throughput of 62 sample/hr. The proposed method was successfully applied for determining PHE in serum samples and pharmaceutical formulations, the interference of excipients was studied. The mechanism of the chemical reaction has been proposed. When the suggested method's results were compared to those provided by a British Pharmacopeia reference method, there was no discernible difference between the two at the 95 percent confidence level.

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Section: Methods Validationmentioning

confidence: 99%

A New Approach for Developing Spectrophotometric Determination of Phenylephrine Drug in Pure, Pharmaceutics and Serum Samples Using Sodium Periodate as Oxidizing Agent via a Green Method of CFIA/Merging Zone Technique

Hamed,

Qassim

2023

Baghdad Sci.J

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A new green method for indirect determination of ferric ions in biological samples using Ascorbic acid as reducing agent via the development of CFIA system

Qassim

Hamed

2021

J. Phys.: Conf. Ser.

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A simple, sensitive, automated and environmentally friendly FI/MZ technique was suggested for the indirect determination of iron (III) as ferric chloride in bulk and biological. These method involve the reduction of Fe (III) to Fe (II) using ascorbic acid as reducing agent, the reduced ion was reacted with 1,10- phenanthroline as a selective organic reagent to form red-orange complex, measured at λ=510 nm. The complexation ratio between matel ion with ligand was 1:3 ratio (M: L). The colored product obeyed Beer’s Law with linear ranges 1-30 and 8-75 μg/mL with detection limits 1.02, 0.28 μg/mL for batch and FIA/MZ methods, respectively. The rate of sampling was 54 sample/h, the %RSD less than 2% and the recovery was about 99%. The developed technique was simply and low cost with high throughput, it provides the use of an aqueous medium as carrier of chemicals in flow system that is nontoxic and causes no pollution, thereby belonging to green chemistry. The proposed procedure can be successfully applied to estimate the content of Iron (III) in biological samples. The results of estimation are satisfactory as compared with those given by a reference method, showed the new method to be accurate and precise at the 95% confidence level.

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A Novel Approach of CFIA Technique for Assaying of Furosemide (Sulfa Drug) as Antibacterial Agent in Pharmaceutical and Biological Samples Using Potassium Ferricyanide as Oxidizing Agent

Ajam,

Basheer

2023

IHJPAS

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Furosemide drug determination in pharmaceutical and biological urine samples using a novel continuous flow-injection analysis technique that is simple, rapid, sensitive and economical. The complex formed by the reaction of furosemide and O-phenylenediamine with oxidative agent K3[Fe(CN)6] to produce an orange-yellow colored product at 460 nm was the basis for the proposed method. The proposed method’s linearity ranges (3-100) μg.mL-1and (1-50) μg.mL-1 for CFIA/merging zone methods and batch .The detection limit and Limit of quantification values were 2.7502 μg.mL-1 and 9.1697 μg.mL-1 the relative standard deviation was 0.7143 %, and the average recovery is 98.80% with a verified sample throughput of 73 h-1 . The new approach was effectively employed to determination of furosemide the presence of in the pure, biological, and pharmaceutical samples.

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Spectrophotometric Determination of Co(II) in Vitamin B12 Using2-(biphenyl-4-yl)-3-((2-(2,4-dinitrophenyl) hydrazono)methyl) imidazo [1,2-a]pyridine as Ligand by Flow Injection–Merging Zone Analysis

Cited by 3 publications

References 10 publications

A New Approach for Developing Spectrophotometric Determination of Phenylephrine Drug in Pure, Pharmaceutics and Serum Samples Using Sodium Periodate as Oxidizing Agent via a Green Method of CFIA/Merging Zone Technique

A New Approach for Developing Spectrophotometric Determination of Phenylephrine Drug in Pure, Pharmaceutics and Serum Samples Using Sodium Periodate as Oxidizing Agent via a Green Method of CFIA/Merging Zone Technique

A new green method for indirect determination of ferric ions in biological samples using Ascorbic acid as reducing agent via the development of CFIA system

A Novel Approach of CFIA Technique for Assaying of Furosemide (Sulfa Drug) as Antibacterial Agent in Pharmaceutical and Biological Samples Using Potassium Ferricyanide as Oxidizing Agent

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