Spectroscopic and photophysical studies of the binding interactions between copper phenanthroline complexes and RNA

Meadows, Kelley A.; Liu, Fang; Sou, Jenny; Hudson, Brian P.; McMillin, David R.

doi:10.1021/ic00065a020

Cited by 85 publications

(47 citation statements)

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“…1.8-1.9, indicating that the DNA was sufficiently free of protein and the concentration was determined by the UV absorbance at 260 nm (ε = 6600 M −1 cm −1 ). 26 The UV-Vis spectra were obtained on a Perkin-Elmer Lambda 35 or 25 double beam spectrophotometer, using 1.0 cm path-length quartz cuvettes (3.0 mL). Fluorescence measurements were performed on a RF-1501 PC spectrofluorometer (Shimadzu, Japan).…”

Section: Uv-vis Dna Interactionsmentioning

confidence: 99%

Synthesis and structures of a pincer-type rhodium(iii) complex: reactivity toward biomolecules

et al. 2016

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with 22mer GG duplex DNA. In addition, a higher reactivity is achieved with a DNA duplex with a centrally located GG-sequence than with a 22GTG duplex DNA, in which the GG-sequence is separated by a T base. Furthermore, the interaction of this metal complex 1 with calf thymus DNA (CT-DNA) and bovine serum albumin (BSA) was examined by absorption (UV-Vis) and emission spectral studies (EthBr displacement studies). Overall, the studied complex exhibited good DNA and BSA interaction ability.

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Section: Uv-vis Dna Interactionsmentioning

confidence: 99%

Synthesis and structures of a pincer-type rhodium(iii) complex: reactivity toward biomolecules

et al. 2016

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“…The concentration of DNA was calculated on the basis of extinction coefficient 6600 M −1 cm −1 at 260 nm. 23 The purification of DNA by phenol extraction methods improved the ratio of UV absorbance at 260 and 280 nm A 260 /A 280 ca. 1.8, indicating that DNA was satisfactory free from proteins.…”

Section: Physical Measurementsmentioning

confidence: 99%

DNA Binding Properties of Two Ruthenium(III) Complexes Containing Schiff Bases Derived from Salicylaldehyde: Spectroscopic and Electrochemical Evidence of CT DNA Intercalation

et al. 2013

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Abstract. The interaction of CT DNA by two anionic Ru(III) complexes with N-substituted salicylidenimine ligands was investigated by spectroscopic titration and cyclic voltammetry. The result gives a surprising evidence for intercalation of DNA by the negatively charged complex species containing non typical intercalating ligands with K b of order 10 4 M −1 . Na[RuCl 2 (N-R-5-X-salim) 2 ], where R represents butyl or phenyl and X = H, Cl, were characterized on the basis of elemental analysis, MALDI-TOF mass spectrometry, infrared, UV / visible spectroscopic measurements and cyclic voltammetry. (doi: 10.5562/cca2216)

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“…3,19,26 Despite the lack of any direct structural evidence, the exciplex formation hypothesis was supported by the correlation between accessibility of the cuprous center by the solvent and the luminescence lifetime, and was widely accepted. 3,19,[27][28][29] Recent contributions from our laboratory using laser-initiated time-resolved x-ray absorption spectroscopy (LITR-XAS) have confirmed the presence of additional coordination to the copper center by a solvent molecule (or counter ion) for photoexcited [Cu I (dmp) 2 ] + in both noncoordinating toluene 30 and strongly coordinating acetonitrile. 31 The interaction strength with the solvent molecule is much weaker in the former and stronger in the latter and is supported by the differentiation of the average copper to ligand distance in the thermally equilibrated 3 MLCT state.…”

Section: Introductionmentioning

confidence: 99%

Ultrafast Structural Rearrangements in the MLCT Excited State for Copper(I) bis-Phenanthrolines in Solution

et al. 2007

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Ultrafast excited state structural dynamics of [Cu I (dmp) 2 ] + (dmp = 2,9-dimethyl-1,10-phenanthroline) have been studied to identify structural origins of transient spectroscopic changes during the photoinduced metal-to-ligand-charge-transfer (MLCT) transition that induces an electronic configuration change from Cu(I) (3d 10 ) to Cu(II) (3d 9 ). This study has important connections with the flattening of the Franck-Condon state tetrahedral geometry and the ligation of Cu(II)* with the solvent observed in the thermally equilibrated MLCT state by our previous laser-initiated time-resolved x-ray absorption spectroscopy (LITR-XAS) results. To better understand the structural photodynamics of

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Spectroscopic and photophysical studies of the binding interactions between copper phenanthroline complexes and RNA

Cited by 85 publications

References 0 publications

Synthesis and structures of a pincer-type rhodium(iii) complex: reactivity toward biomolecules

Synthesis and structures of a pincer-type rhodium(iii) complex: reactivity toward biomolecules

DNA Binding Properties of Two Ruthenium(III) Complexes Containing Schiff Bases Derived from Salicylaldehyde: Spectroscopic and Electrochemical Evidence of CT DNA Intercalation

Ultrafast Structural Rearrangements in the MLCT Excited State for Copper(I) bis-Phenanthrolines in Solution

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