2002
DOI: 10.1016/s0022-2313(02)00344-7
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Spectroscopic studies of microenvironment dictated structural forms of piroxicam and meloxicam

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Cited by 53 publications
(48 citation statements)
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“…It is important to note that the T fus value is similar to that reported by Sathesh-Babu et al (530 K) but the H fus value differs considerably from that reported by these authors (71.3 kJ mol −1 ) [13]. The observed discrepancies could be attributed to different polymorphs employed in each case, as has been indicated in the literature [14]. According to Luger et al meloxicam presents polymorphism with two polymorphic forms, I (enol form) and II (zwitterions form) [15].…”
Section: X-ray Diffraction Analysissupporting
confidence: 82%
See 1 more Smart Citation
“…It is important to note that the T fus value is similar to that reported by Sathesh-Babu et al (530 K) but the H fus value differs considerably from that reported by these authors (71.3 kJ mol −1 ) [13]. The observed discrepancies could be attributed to different polymorphs employed in each case, as has been indicated in the literature [14]. According to Luger et al meloxicam presents polymorphism with two polymorphic forms, I (enol form) and II (zwitterions form) [15].…”
Section: X-ray Diffraction Analysissupporting
confidence: 82%
“…Eq. (14) for the correlation volume requires iteration, because it depends on the local mole fractions. The numerical values are valid for the radius of the solute r 3 in nm.…”
Section: Preferential Solvation Of Melmentioning
confidence: 99%
“…[1,2]. Some of these NSAIDs also have interesting spectroscopic properties that are sensitive to their microenvironment and can be used effectively as reporter of their interaction with biomolecules [3][4][5]. Indomethacin (N-(parachlorobenzoyl)-5-methoxy-2-methylindoole-3-acetic acid) ( Figure 1) is a traditional painkiller whose spectroscopic and photochemical properties have been well studied [6].…”
Section: Introductionmentioning
confidence: 99%
“…It attracts the researchers' attention because of its rich tautomeric behavior [11][12][13][14][15][16][17]. The fact that PX can convert between different forms is especially important for delivery and action of this drug, because only the neutral form of oxicam drugs are suggested to be medically active [11,12].…”
Section: Introductionmentioning
confidence: 99%