Spinal Necrosis and Softening of Obscure Origin

JAFFE, DANIEL

doi:10.1001/archneurpsyc.1943.02290170053004

Cited by 35 publications

(4 citation statements)

References 25 publications

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“…In 13 of 38 cases reported by Jaffe and Freeman [10], bacterial infection preceded the onset of the condition. In many cases, there is a lymphocytic infiltration in the spinal cord and meninges.…”

Section: Discussionmentioning

confidence: 94%

“…In both cases, white and gray matter showed sym metrical necrotic processes. Case 3 of Morersch and Kernohan [20] had squamous cell carcinoma of the skin and case 2 of Jaffe and Free man [10] had an associated malignant disease in the thyroid. Mathieson's [17] case which was associated with carcinoma of the breast, showed pathology in the cervical cord as well as in the pons and medul la.…”

Section: Discussionmentioning

confidence: 99%

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Acute Necrotic Myelopathy in Association with Lymphoma Cells of the Reticulo-Endothelial System, Acute Torticollis, and Recurrent Cardiac Arrest

Nishida¹,

Ziegler²

1973

Stereotact Funct Neurosurg

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A case of acute necrotic myelopathy (ANM) is reported in conjunction with a noninvasive reticular type of lymphoma. The clinical course was characterized by two rare phenomena: (1) acute torticollis occurred as an initial manifestation, probably as a result of irritation of the dorsal root or dorsal horn; (2) recurrent cardiac arrest occurred late in the course, probably as a result of hypersensitivity of the sensors of postural change. The occurrence of ANM in patients with neoplasia is reviewed and it is concluded that the nature of the association is unknown. Some evidence points to abnormal immunological reactions leading to vascular damage and cord ischemia.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Acute Necrotic Myelopathy in Association with Lymphoma Cells of the Reticulo-Endothelial System, Acute Torticollis, and Recurrent Cardiac Arrest

Nishida¹,

Ziegler²

1973

Stereotact Funct Neurosurg

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“…Acute transverse myeli tis mortality was seemingly high in the older case reports [26,27], but has been infrequent in recent years.…”

Section: Introductionmentioning

confidence: 95%

Incidence of Acute Transverse Myelitis in Rochester, Minnesota, 1970–1980, and Implications with Respect to Influenza Vaccine

1982

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Acute transverse myelitis is a clinical entity characterized by acute onset of nonrecurrent, bilateral but not necessarily symmetrical, cross-sectional sensorimotor involvement of the spinal cord. Vascular lesions, inflammatory (mainly viral) disorders, and necrotic myelopathy as a remote effect of cancer have been reported as possible etiologic factors. Epidemiologic data on the disease are scarce. From the Mayo Clinic records-linkage system, 5 cases fulfilling the diagnostic criteria of acute transverse myelitis were collected during the study period 1970–1980 among the residents of Rochester, Minn. (USA), providing a mean annual incidence rate of 0.82 per 100,000 person-years, or 1.2 per 100,000 person-years for those 18 years of age and over. None of the cases described were post-vaccinal; an estimate of the number of cases occurring fortuitously following the swine flu vaccination program of 1976 in the USA is provided.

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“…[1][2][3] The terms acute transverse myelitis (ATM) and acute transverse myelopathy have been used interchangeably to describe a syndrome characterized by anterior and posterior (hence transverse) spinal cord impairment resulting in weakness, a sensory level, and autonomic dysfunction. Possible causes include vascular, infectious, neoplastic, collagen vascular, iatrogenic, and autoimmune etiologies.…”

mentioning

confidence: 99%