Splenomegaly in Schistosomiasis Mansoni

Kloetzel, Kurt

doi:10.4269/ajtmh.1962.11.472

Cited by 60 publications

(16 citation statements)

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“…Untill very recently it meant that this individual had hepatosplenic schistosomiasis, also considered or called by some authors, the severe form of the disease (Kloetzel 1962). Based on this concept a series of investigations of prevalence, and correlations with age, gender, skin color, worm burden, different aspects of morbidity before and after treatment, and a series of immunological studies have been developed and reported (Lambertucci 1993).…”

Section: Discussionmentioning

confidence: 99%

Hepatosplenic schistosomiasis in field-based studies: a combined clinical and sonographic definition

Lambertucci

Cota

Pinto-Silva

et al. 2001

Mem. Inst. Oswaldo Cruz

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Section: Discussionmentioning

confidence: 99%

Hepatosplenic schistosomiasis in field-based studies: a combined clinical and sonographic definition

Lambertucci

Cota

Pinto-Silva

et al. 2001

Mem. Inst. Oswaldo Cruz

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“…It is easier to pinpoint the alterations caused by the disease in the walls of the gallbladder, the periportal thickening, and to identify the abdominal venous system. Until very recently the diagnosis of hepatosplenic schistosomiasis was based on the evaluation of hepatosplenomegaly by abdominal palpation 7 . In the last two decades, however, studies comparing spleen palpation to more accurate methods for the diagnosis of spleen enlargement have shown the limitations of abdominal palpation 3 6 10 .…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging and ultrasound in hepatosplenic schistosomiasis mansoni

Lambertucci

Silva

Andrade

et al. 2004

Rev. Soc. Bras. Med. Trop.

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“…A palpable liver has been described in different proportions of normal people. Riedel's lobe (a tongue-like process occasionally extending downward from the right lobe of the liver laterally to the gallbladder) should also be considered in cases of increased right liver lobe size in schistosomiasis [16][17][18][19] .…”

Section: Clinical Definition Of Hepatosplenicmentioning

confidence: 99%

Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools

Lambertucci

2014

Rev. Soc. Bras. Med. Trop.

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Different aspects of hepatosplenic schistosomiasis are revisited here. Manson's schistosomiasis causes periportal fi brosis and portal hypertension in approximately 6% of infected subjects, usually with preservation of their hepatic function. The assessment of liver involvement is of major importance in determining the prognosis and risk of complications from schistosomiasis, such as upper digestive bleeding secondary to variceal rupture. For many years, the diagnosis of hepatosplenic schistosomiasis and liver fi brosis was made by abdominal palpation and the fi nding of liver and/or spleen enlargement. However, there is no consensus regarding the clinical parameters of the liver and spleen to be considered in this physical evaluation. For the last three decades, abdominal ultrasound (US) has become the best imaging technique to evaluate liver fi brosis caused by schistosomiasis mansoni. However, US is a subjective procedure and is therefore examiner-dependent. Magnetic resonance imaging (MRI) fi ndings have provided valuable information in addition to ultrasound and clinical examination. The combination of a comprehensive history and physical examination, basic laboratory tests (a stool examination for Schistosoma mansoni eggs and a blood cell count), biomarkers for liver fi brosis/portal hypertension and imaging methods seem to offer the best approach for evaluating patients with this disease. In situations where research is involved or in patients with severe disease, MRI may be considered.

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Splenomegaly in Schistosomiasis Mansoni

Cited by 60 publications

References 0 publications

Hepatosplenic schistosomiasis in field-based studies: a combined clinical and sonographic definition

Hepatosplenic schistosomiasis in field-based studies: a combined clinical and sonographic definition

Magnetic resonance imaging and ultrasound in hepatosplenic schistosomiasis mansoni

Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools

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