Standardization of Ayurvedic polyherbal formulation, Kutajastaka Pravahi Kvatha

Tiwari, Ashok Kumar; Dwivedi, Neelesh; Tripathi, Manoj Kumar; Tiwari, Aakanksha; Ahirwar, Pawan Kumar; Tripathi, Sharda Prasad

doi:10.5958/0975-4385.2016.00019.4

Cited by 2 publications

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“…Standard pharmacopoeial methods [7] were used to investigate the raw materials of BrihatyadiKwatha. Determination of alcohol soluble extractives, water soluble extractives, total ash, acid insoluble ash, loss on drying, and pH determinations were conducted.…”

Section: Preliminary Physical and Phytochemical Evaluationmentioning

confidence: 99%

Pharmacognostic, physicochemical, and TLC Characterisation of Brhatyadi Kwatha used in Kerala

2022

KJA

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Brihatyadi Kwatha (BK) a popular Ayurvedic polyherbal decoction for urinary problems is a formulation of five roots -Salaparni, Prisniparni, Brihati, Kantakari and Gokshura. Sahasrayoga, adopting Ashtanga Hrdaya describes the drug ratio as 1:1:1:1:2 respectively, but some formularies consider ratio of the last drug as 4 and 8. The source of Prisniparni is Desmodium gangeticum (L.) DC in Kerala where as it is Uraria picta (Jacq.)DC in north. This diversity in source plants and proportion of ingredients can create variability in product standards. Currently there is no specific standard prescribed for BK in Ayurveda Formulary of India. Hence, this study is taken up as step towards standardisation of Brihatyadi Kwatha. The study aims to determine characteristic Pharmacognostic and Physicochemical parameters and TLC profile of ingredients as well as the end product -two variants of Brihatyadi Kwatha, to set standards. Ingredient drugs of BK were subjected to macroscopic, microscopic, physicochemical analysis. Ingredients and products were subjected to Thin Layer Chromatography Characteristic features of the analyses were recorded. R f values in the TLC profile demonstrated presence of all ingredients of BK. The findings may be useful as standards for quality control of Brihatyadi Kwatha.

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Section: Preliminary Physical and Phytochemical Evaluationmentioning

confidence: 99%

Pharmacognostic, physicochemical, and TLC Characterisation of Brhatyadi Kwatha used in Kerala

2022

KJA

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Polyherbal Formulation Development and Assessment of its Potential against Urolithiasis (Mutrakricchra) by In-Vitro Technique

Sharma

Baghel

Mittal

et al. 2021

RJPT

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Background: Urolithiasis (Mutrakricchra) is an age-old disorder which has multi-factorial etiological as well as associated with re-occurrence. It is standout among the most troubling disorders related to urinary tract. Acharya Sushruta, a pioneer in the art of surgery, described the root causes and management of urolithiasis (Mutrakricchra). In present day restorative practice, a lot of the management/treatment choices are available which begins from the utilization of uresis-elevating specialist to dietary or nourishing enhancement consumption. Methodologies created by amalgamating the Ayurvedic principle/concept with current medicinal practice are a promising methodology and even effectively used for the management of urolithiasis (Mutrakricchra). Objective: To prepare a poly herbal formulation and evaluate its potential against Urolithiasis (Mutrakrichra) by In-Vitro technique. Materials and Methods: Trikantakadi kvatha was prepared as per the methodology described in Ayurveda Sar Samgraha. Prepared Trikantakadi kvatha was converted in ghan by evaporating the watery portion and Trikantakadi kvatha ghan vati (TKGV) were prepared by adding excipients in prepared ghan. Various parameters performed for physicochemical and phytochemical characterization of raw material (crude herbs) and prepared tablet dosage form. Results: Physicochemical and phytochemical investigations are not shown any remarkable variations with prepared tablet dosage forms when compared with Trikantakadi kvatha churn. Prepared tablet (TKGV) shows crystal inhibition with passage of time the percentage of crystal inhibition also varied accordingly in the drug concentration (1000 µg/ml) showed the maximum 76.25% crystal inhibition. Conclusion: The prepared dosages forms were not exhibited any remarkable variation during physicochemical, phytochemical and thin-layer chromatography studies. However, the Trikantakadi kvatha ghan vati (TKGV) developed dosage forms are more stable than kvatha (Decoction) and produces promising result against Urolithiasis (Mutrakrichra).

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Standardization of Ayurvedic polyherbal formulation, Kutajastaka Pravahi Kvatha

Cited by 2 publications

References 0 publications

Pharmacognostic, physicochemical, and TLC Characterisation of Brhatyadi Kwatha used in Kerala

Pharmacognostic, physicochemical, and TLC Characterisation of Brhatyadi Kwatha used in Kerala

Polyherbal Formulation Development and Assessment of its Potential against Urolithiasis (Mutrakricchra) by In-Vitro Technique

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